FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2116040329> ?p ?o ?g. }

• W2116040329 endingPage "1432" @default.
• W2116040329 startingPage "1423" @default.
• W2116040329 abstract "Studies of the Antennapedia-class homeobox genes suggest that specific combinations of these transcription factors play a role in defining neuronal identities. We examined the expression of these genes in the leech Hirudo medicinalis, an organism well-suited for neurobiological research at the level of identified neurons. Leeches contain at least as many Antennapedia-class and related genes as insects do, despite the apparently lower complexity of the leech body plan. The CNS expression patterns of two Antennapedia-class leech homeobox genes (Lox genes) were examined in detail. Lox1 is expressed during early gangliogenesis in only one pair of transient neurons present in every segment (the Bipolar cells) and, at later stages of embryonic development, in 15–20 pairs of central neurons repeated in most segments. The monoclonal antibody Laz1-1 identified two pairs of Lox1-expressing neurons as the Bipolar cells and the L1 neurons. The Bipolar cells extended processes in the primordia of the longitudinal connective nerves and later degenerated. The L1 neurons were detected late in gangliogenesis and became stable neurons. Lox2 is expressed in an iterated set of neurons in the posterior two-thirds of the CNS. On the basis of cell body position and relative size, two pairs of Lox2-expressing cells were identified as the RPE-like neurons and the CV motor neurons. Other Lox genes are also expressed in segmentally repeated subpopulations of neurons. These neuronal subpopulations appear to be different from one another but partially overlapping. Different combinations of Lox genes that may be expressed in individual cells could in theory generate enough variability to specify all central neurons in a leech ganglion. © 1993 John Wiley & Sons, Inc." @default.
• W2116040329 created "2016-06-24" @default.
• W2116040329 creator A5002668204 @default.
• W2116040329 creator A5059026294 @default.
• W2116040329 creator A5060934104 @default.
• W2116040329 creator A5073813195 @default.
• W2116040329 date "1993-10-01" @default.
• W2116040329 modified "2023-09-26" @default.
• W2116040329 title "Antennapedia-Class homeobox genes define diverse neuronal sets in the embryonic CNS of the leech" @default.
• W2116040329 cites W1565800544 @default.
• W2116040329 cites W1589289885 @default.
• W2116040329 cites W1638741749 @default.
• W2116040329 cites W1861576877 @default.
• W2116040329 cites W1974276803 @default.
• W2116040329 cites W1978629467 @default.
• W2116040329 cites W2006464750 @default.
• W2116040329 cites W2006788765 @default.
• W2116040329 cites W2007755249 @default.
• W2116040329 cites W2009851083 @default.
• W2116040329 cites W2020160255 @default.
• W2116040329 cites W2024250315 @default.
• W2116040329 cites W2043889579 @default.
• W2116040329 cites W2072570820 @default.
• W2116040329 cites W2077497255 @default.
• W2116040329 cites W2082398682 @default.
• W2116040329 cites W2086467423 @default.
• W2116040329 cites W2091626902 @default.
• W2116040329 cites W2093055721 @default.
• W2116040329 cites W2101748552 @default.
• W2116040329 cites W2113162819 @default.
• W2116040329 cites W2122468638 @default.
• W2116040329 cites W2162742843 @default.
• W2116040329 cites W2163350560 @default.
• W2116040329 cites W2176692887 @default.
• W2116040329 cites W229175776 @default.
• W2116040329 cites W4206062333 @default.
• W2116040329 doi "https://doi.org/10.1002/neu.480241012" @default.
• W2116040329 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7901325" @default.
• W2116040329 hasPublicationYear "1993" @default.
• W2116040329 type Work @default.
• W2116040329 sameAs 2116040329 @default.
• W2116040329 citedByCount "21" @default.
• W2116040329 countsByYear W21160403292018 @default.
• W2116040329 countsByYear W21160403292023 @default.
• W2116040329 crossrefType "journal-article" @default.
• W2116040329 hasAuthorship W2116040329A5002668204 @default.
• W2116040329 hasAuthorship W2116040329A5059026294 @default.
• W2116040329 hasAuthorship W2116040329A5060934104 @default.
• W2116040329 hasAuthorship W2116040329A5073813195 @default.
• W2116040329 hasConcept C104317684 @default.
• W2116040329 hasConcept C111039654 @default.
• W2116040329 hasConcept C121587040 @default.
• W2116040329 hasConcept C136764020 @default.
• W2116040329 hasConcept C145103041 @default.
• W2116040329 hasConcept C169760540 @default.
• W2116040329 hasConcept C180746962 @default.
• W2116040329 hasConcept C2775926713 @default.
• W2116040329 hasConcept C2777831001 @default.
• W2116040329 hasConcept C2780172944 @default.
• W2116040329 hasConcept C41008148 @default.
• W2116040329 hasConcept C529278444 @default.
• W2116040329 hasConcept C54355233 @default.
• W2116040329 hasConcept C86339819 @default.
• W2116040329 hasConcept C86803240 @default.
• W2116040329 hasConceptScore W2116040329C104317684 @default.
• W2116040329 hasConceptScore W2116040329C111039654 @default.
• W2116040329 hasConceptScore W2116040329C121587040 @default.
• W2116040329 hasConceptScore W2116040329C136764020 @default.
• W2116040329 hasConceptScore W2116040329C145103041 @default.
• W2116040329 hasConceptScore W2116040329C169760540 @default.
• W2116040329 hasConceptScore W2116040329C180746962 @default.
• W2116040329 hasConceptScore W2116040329C2775926713 @default.
• W2116040329 hasConceptScore W2116040329C2777831001 @default.
• W2116040329 hasConceptScore W2116040329C2780172944 @default.
• W2116040329 hasConceptScore W2116040329C41008148 @default.
• W2116040329 hasConceptScore W2116040329C529278444 @default.
• W2116040329 hasConceptScore W2116040329C54355233 @default.
• W2116040329 hasConceptScore W2116040329C86339819 @default.
• W2116040329 hasConceptScore W2116040329C86803240 @default.
• W2116040329 hasIssue "10" @default.
• W2116040329 hasLocation W21160403291 @default.
• W2116040329 hasLocation W21160403292 @default.
• W2116040329 hasOpenAccess W2116040329 @default.
• W2116040329 hasPrimaryLocation W21160403291 @default.
• W2116040329 hasRelatedWork W151525163 @default.
• W2116040329 hasRelatedWork W1830151389 @default.
• W2116040329 hasRelatedWork W1978629467 @default.
• W2116040329 hasRelatedWork W1988933057 @default.
• W2116040329 hasRelatedWork W1995320668 @default.
• W2116040329 hasRelatedWork W1997497353 @default.
• W2116040329 hasRelatedWork W2049035348 @default.
• W2116040329 hasRelatedWork W2116040329 @default.
• W2116040329 hasRelatedWork W2134764336 @default.
• W2116040329 hasRelatedWork W2171498188 @default.
• W2116040329 hasVolume "24" @default.
• W2116040329 isParatext "false" @default.
• W2116040329 isRetracted "false" @default.
• W2116040329 magId "2116040329" @default.

• next