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- W2116071839 abstract "In this work, we describe the fabrication of an ultrasensitive electrochemical biosensor for the determination of the mercury(II) ion (Hg2+) in aqueous solution. The biosensor is based on a glassy carbon electrode (GCE) modified with multi-walled carbon nanotubes (MWCNTs) and gold nanoparticles (Au-NPs). Probe DNA (HS-DNA) was then covalently linked to the surface of the Au-NPs/MWCNTs via Au–S bonds. In the presence of Hg2+, the probe DNA can hybridize with the target DNA to form duplex DNA via the strong and specific binding of Hg2+ by two DNA thymine bases (T–Hg2+–T). Differential pulse voltammetry was employed to investigate the hybridization process and measure the changes in peak current intensity of intercalated adriamycin in the presence of different concentrations of Hg2+. The increase in peak current intensity of adriamycin was linear with an increase in the concentration of Hg2+ in the range from 0.1 to 20 nmol L−1 with a detection limit of 0.03 nmol L−1 (S/N = 3) under the optimal conditions. In addition, the biosensor exhibits good selectivity, stability and reproducibility." @default.
- W2116071839 created "2016-06-24" @default.
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- W2116071839 date "2012-01-01" @default.
- W2116071839 modified "2023-10-02" @default.
- W2116071839 title "An ultrasensitive electrochemical mercury(ii) ion biosensor based on a glassy carbon electrode modified with multi-walled carbon nanotubes and gold nanoparticles" @default.
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- W2116071839 doi "https://doi.org/10.1039/c2ay25634g" @default.
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