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- W2116163670 endingPage "492" @default.
- W2116163670 startingPage "484" @default.
- W2116163670 abstract "Intracerebral haemorrhage is a complication of thrombolytic therapy for acute myocardial infarction, pulmonary embolism, and ischaemic stroke. There is increasing evidence that cerebral amyloid angiopathy (CAA), which itself can cause haemorrhage (CAAH), may be a risk factor for thrombolysis-related intracerebral haemorrhage. CAAH and thrombolysis-related intracerebral haemorrhage share some clinical features, such as predisposition to lobar or superficial regions of the brain, multiple haemorrhages, increasing frequency with age, and an association with dementia. In vitro work showed that accumulation of amyloid-beta peptide causes degeneration of cells in the walls of blood vessels, affects vasoactivity, and improves proteolytic mechanisms, such as fibrinolysis, anticoagulation, and degradation of the extracellular matrix. In a mouse model of CAA there is a low haemorrhagic threshold after thrombolytic therapy compared with that in wild-type mice. To date only a small number of anecdotal clinicopathological relations have been reported; neuroimaging advances and further study of the frequency and role of CAA in patients with thrombolysis-related intracerebral haemorrhage are required." @default.
- W2116163670 created "2016-06-24" @default.
- W2116163670 creator A5037948029 @default.
- W2116163670 creator A5053163430 @default.
- W2116163670 date "2004-08-01" @default.
- W2116163670 modified "2023-09-26" @default.
- W2116163670 title "Cerebral amyloid angiopathy and thrombolysis-related intracerebral haemorrhage" @default.
- W2116163670 cites W101335387 @default.
- W2116163670 cites W1484129406 @default.
- W2116163670 cites W148771838 @default.
- W2116163670 cites W1496503766 @default.
- W2116163670 cites W1551767576 @default.
- W2116163670 cites W1594119953 @default.
- W2116163670 cites W1617304195 @default.
- W2116163670 cites W1619610860 @default.
- W2116163670 cites W1966030100 @default.
- W2116163670 cites W1968954730 @default.
- W2116163670 cites W1969095640 @default.
- W2116163670 cites W1969437735 @default.
- W2116163670 cites W1970999274 @default.
- W2116163670 cites W1972122682 @default.
- W2116163670 cites W1972942629 @default.
- W2116163670 cites W1974059538 @default.
- W2116163670 cites W1974103269 @default.
- W2116163670 cites W1975848755 @default.
- W2116163670 cites W1978873309 @default.
- W2116163670 cites W1980786936 @default.
- W2116163670 cites W1982206682 @default.
- W2116163670 cites W1983670592 @default.
- W2116163670 cites W1983933902 @default.
- W2116163670 cites W1985093052 @default.
- W2116163670 cites W1985542320 @default.
- W2116163670 cites W1990427131 @default.
- W2116163670 cites W1991277746 @default.
- W2116163670 cites W1992953826 @default.
- W2116163670 cites W1998801224 @default.
- W2116163670 cites W2000917982 @default.
- W2116163670 cites W2001020786 @default.
- W2116163670 cites W2001688761 @default.
- W2116163670 cites W2002172383 @default.
- W2116163670 cites W2003160901 @default.
- W2116163670 cites W2004715168 @default.
- W2116163670 cites W2004964289 @default.
- W2116163670 cites W2006409771 @default.
- W2116163670 cites W2007402264 @default.
- W2116163670 cites W2011112318 @default.
- W2116163670 cites W2014594084 @default.
- W2116163670 cites W2014667778 @default.
- W2116163670 cites W2018080763 @default.
- W2116163670 cites W2018773958 @default.
- W2116163670 cites W2021390563 @default.
- W2116163670 cites W2022298496 @default.
- W2116163670 cites W2024115648 @default.
- W2116163670 cites W2024191170 @default.
- W2116163670 cites W2024276472 @default.
- W2116163670 cites W2024607985 @default.
- W2116163670 cites W2025313184 @default.
- W2116163670 cites W2027157730 @default.
- W2116163670 cites W2032020642 @default.
- W2116163670 cites W2033403172 @default.
- W2116163670 cites W2036920551 @default.
- W2116163670 cites W2037212878 @default.
- W2116163670 cites W2040859034 @default.
- W2116163670 cites W2041396523 @default.
- W2116163670 cites W2042267799 @default.
- W2116163670 cites W2042853733 @default.
- W2116163670 cites W2049664082 @default.
- W2116163670 cites W2051182982 @default.
- W2116163670 cites W2052987015 @default.
- W2116163670 cites W2054931992 @default.
- W2116163670 cites W2055079541 @default.
- W2116163670 cites W2055763065 @default.
- W2116163670 cites W2059804089 @default.
- W2116163670 cites W2059864379 @default.
- W2116163670 cites W2061467737 @default.
- W2116163670 cites W2064810347 @default.
- W2116163670 cites W2068052351 @default.
- W2116163670 cites W2068808615 @default.
- W2116163670 cites W2069768603 @default.
- W2116163670 cites W2072682191 @default.
- W2116163670 cites W2074747084 @default.
- W2116163670 cites W2076453964 @default.
- W2116163670 cites W2077570570 @default.
- W2116163670 cites W2079442692 @default.
- W2116163670 cites W2081990092 @default.
- W2116163670 cites W2087508226 @default.
- W2116163670 cites W2087529125 @default.
- W2116163670 cites W2088641840 @default.
- W2116163670 cites W2089613059 @default.
- W2116163670 cites W2089989638 @default.
- W2116163670 cites W2090324585 @default.
- W2116163670 cites W2090723320 @default.
- W2116163670 cites W2091450758 @default.
- W2116163670 cites W2091549068 @default.
- W2116163670 cites W2091766797 @default.
- W2116163670 cites W2092243489 @default.
- W2116163670 cites W2102535207 @default.
- W2116163670 cites W2104080769 @default.