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- W2116200665 abstract "Immune memory is the hallmark of adaptive immunity. However, recent studies have shown that natural killer (NK) cells, key components of the innate immune system, also mediate memory responses in mice and humans. Strikingly, memory NK cells were liver-resident in some models, raising the question as to whether the liver is a special organ for the acquisition of NK cell memory. Here, we review the characteristics of NK cell memory by summarizing recent progress and discuss how the liver may generate both the initiation and the recall phase of memory. We propose that the liver may have unique precursors for memory NK cells, which are developmentally distinct from NK cells derived from bone marrow." @default.
- W2116200665 created "2016-06-24" @default.
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- W2116200665 date "2013-04-08" @default.
- W2116200665 modified "2023-09-26" @default.
- W2116200665 title "Memory NK cells: why do they reside in the liver?" @default.
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- W2116200665 doi "https://doi.org/10.1038/cmi.2013.8" @default.
- W2116200665 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4012773" @default.
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