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• W2116333663 abstract "Previously, we studied the surface expression of LFA-1 (CD 11 a/CD 18) and ICAM-1 (CD54) in a panel of 16 human T-cell lines and found that those carrying HTLV-1 pro-viruses expressed high levels of ICAM-1. Enhanced expression of ICAM-1 was also seen in fresh leukemic cells from ATL patients. In the present study, we systematically examined the surface expression of 19 different cell-adhesion molecules (CAMs) (the immunoglobulin superfamily, the homing receptors, the integrins, etc.) in a panel of 20 human T-cell lines (6 HTLV-1-negative lines and 14 HTLV-1-positive lines). The surface expression of LFA-3 (CD58) was constantly enhanced in HTLV-1-positive T-cell lines except for MT-1, an ATL-derived cell line, which was devoid of a number of CAMs including ICAM-1. LFA-3 proteins and mRNA were found at strongly increased levels in HTLV-1 -positive T-cell lines." @default.
• W2116333663 created "2016-06-24" @default.
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• W2116333663 date "1993-11-11" @default.
• W2116333663 modified "2023-09-30" @default.
• W2116333663 title "Enhanced expression of LFA-3 on human T-cell lines and leukemic cells carrying human T-cell-leukemia virus type 1" @default.
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• W2116333663 doi "https://doi.org/10.1002/ijc.2910550520" @default.
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