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- W211634417 abstract "This chapter focuses on the immunotherapy of acute myeloblastic leukemia (AML). On the surface of many AML cells, there are some foreign proteins, which may distinguish them from the normal cells of the tissue of origin. The most logical way in which to immunize an animal against a tumor is to do so using the specific tumor antigen. Membrane extracts may be used for this purpose, but this method suffers from the disadvantage that fragile antigenic determinants may be damaged in the extraction procedure. Viable cell suspensions irradiated to prevent implantation offers an alternative means of presenting tumor antigen. To justify the term immunotherapy, an observed therapeutic effect must follow an immunological manipulation. There has been new speculation about the possible mechanism of action of BCG, that is, it stimulates the normal bone marrow and enables the balance between the normal cells and the leukaemic cells to be changed in favor of the former." @default.
- W211634417 created "2016-06-24" @default.
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- W211634417 date "1976-01-01" @default.
- W211634417 modified "2023-10-16" @default.
- W211634417 title "THE IMMUNOTHERAPY OF ACUTE MYELOBLASTIC LEUKAEMIA" @default.
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- W211634417 doi "https://doi.org/10.1016/b978-0-08-021101-5.50024-7" @default.
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