FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2116417070> ?p ?o ?g. }

• W2116417070 endingPage "6790" @default.
• W2116417070 startingPage "6777" @default.
• W2116417070 abstract "Neutralizing antibody is associated with the prevention and clearance of influenza virus infection. Microneutralization (MN) and hemagglutination inhibition (HI) assays are currently used to evaluate neutralizing antibody responses against human and avian influenza viruses, including H5N1. The MN assay is somewhat labor intensive, while HI is a surrogate for neutralization. Moreover, use of replication competent viruses in these assays requires biosafety level 3 (BSL-3) containment. Therefore, a neutralization assay that does not require BSL-3 facilities would be advantageous. Toward this goal, we generated a panel of pseudotypes expressing influenza hemagglutinin (HA) and neuraminidase (NA) and developed a pseudotype-based neutralization (PN) assay. Here we demonstrate that HA/NA pseudotypes mimic release and entry of influenza virus and that the PN assay exhibits good specificity and reveals quantitative difference in neutralizing antibody titers against different H5N1 clades and subclades. Using immune ferret sera, we demonstrated excellent correlation between the PN, MN, and HI assays. Thus, we conclude that the PN assay is a sensitive and quantifiable method to measure neutralizing antibodies against diverse clades and subclades of H5N1 influenza virus." @default.
• W2116417070 created "2016-06-24" @default.
• W2116417070 creator A5001645232 @default.
• W2116417070 creator A5002240899 @default.
• W2116417070 creator A5002715522 @default.
• W2116417070 creator A5003364708 @default.
• W2116417070 creator A5003852242 @default.
• W2116417070 creator A5010124441 @default.
• W2116417070 creator A5042355300 @default.
• W2116417070 creator A5044000598 @default.
• W2116417070 creator A5061722893 @default.
• W2116417070 creator A5070813586 @default.
• W2116417070 creator A5081495564 @default.
• W2116417070 creator A5082521577 @default.
• W2116417070 creator A5084636908 @default.
• W2116417070 date "2009-11-01" @default.
• W2116417070 modified "2023-10-17" @default.
• W2116417070 title "Measurement of neutralizing antibody responses against H5N1 clades in immunized mice and ferrets using pseudotypes expressing influenza hemagglutinin and neuraminidase" @default.
• W2116417070 cites W1533777823 @default.
• W2116417070 cites W186924384 @default.
• W2116417070 cites W1970708694 @default.
• W2116417070 cites W1978335031 @default.
• W2116417070 cites W1981440980 @default.
• W2116417070 cites W1983181891 @default.
• W2116417070 cites W2001089308 @default.
• W2116417070 cites W2013911193 @default.
• W2116417070 cites W2020316997 @default.
• W2116417070 cites W2027374861 @default.
• W2116417070 cites W2028504310 @default.
• W2116417070 cites W2031908280 @default.
• W2116417070 cites W2037709417 @default.
• W2116417070 cites W2061682040 @default.
• W2116417070 cites W2069338024 @default.
• W2116417070 cites W2079424087 @default.
• W2116417070 cites W2079555292 @default.
• W2116417070 cites W2091982662 @default.
• W2116417070 cites W2102335249 @default.
• W2116417070 cites W2110842901 @default.
• W2116417070 cites W2118110185 @default.
• W2116417070 cites W2141848036 @default.
• W2116417070 cites W2145825913 @default.
• W2116417070 cites W2147169218 @default.
• W2116417070 cites W2155467153 @default.
• W2116417070 cites W2155577789 @default.
• W2116417070 cites W2316262719 @default.
• W2116417070 doi "https://doi.org/10.1016/j.vaccine.2009.08.056" @default.
• W2116417070 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7115403" @default.
• W2116417070 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19732860" @default.
• W2116417070 hasPublicationYear "2009" @default.
• W2116417070 type Work @default.
• W2116417070 sameAs 2116417070 @default.
• W2116417070 citedByCount "53" @default.
• W2116417070 countsByYear W21164170702012 @default.
• W2116417070 countsByYear W21164170702013 @default.
• W2116417070 countsByYear W21164170702014 @default.
• W2116417070 countsByYear W21164170702015 @default.
• W2116417070 countsByYear W21164170702016 @default.
• W2116417070 countsByYear W21164170702017 @default.
• W2116417070 countsByYear W21164170702021 @default.
• W2116417070 countsByYear W21164170702022 @default.
• W2116417070 countsByYear W21164170702023 @default.
• W2116417070 crossrefType "journal-article" @default.
• W2116417070 hasAuthorship W2116417070A5001645232 @default.
• W2116417070 hasAuthorship W2116417070A5002240899 @default.
• W2116417070 hasAuthorship W2116417070A5002715522 @default.
• W2116417070 hasAuthorship W2116417070A5003364708 @default.
• W2116417070 hasAuthorship W2116417070A5003852242 @default.
• W2116417070 hasAuthorship W2116417070A5010124441 @default.
• W2116417070 hasAuthorship W2116417070A5042355300 @default.
• W2116417070 hasAuthorship W2116417070A5044000598 @default.
• W2116417070 hasAuthorship W2116417070A5061722893 @default.
• W2116417070 hasAuthorship W2116417070A5070813586 @default.
• W2116417070 hasAuthorship W2116417070A5081495564 @default.
• W2116417070 hasAuthorship W2116417070A5082521577 @default.
• W2116417070 hasAuthorship W2116417070A5084636908 @default.
• W2116417070 hasBestOaLocation W21164170701 @default.
• W2116417070 hasConcept C134164806 @default.
• W2116417070 hasConcept C14086860 @default.
• W2116417070 hasConcept C142724271 @default.
• W2116417070 hasConcept C159047783 @default.
• W2116417070 hasConcept C159654299 @default.
• W2116417070 hasConcept C182072434 @default.
• W2116417070 hasConcept C203014093 @default.
• W2116417070 hasConcept C2522874641 @default.
• W2116417070 hasConcept C2777538117 @default.
• W2116417070 hasConcept C2777546802 @default.
• W2116417070 hasConcept C2778692840 @default.
• W2116417070 hasConcept C2779134260 @default.
• W2116417070 hasConcept C2779261636 @default.
• W2116417070 hasConcept C3008058167 @default.
• W2116417070 hasConcept C32611913 @default.
• W2116417070 hasConcept C34343649 @default.
• W2116417070 hasConcept C519248777 @default.
• W2116417070 hasConcept C524204448 @default.
• W2116417070 hasConcept C71924100 @default.
• W2116417070 hasConcept C86803240 @default.
• W2116417070 hasConceptScore W2116417070C134164806 @default.
• W2116417070 hasConceptScore W2116417070C14086860 @default.

• next