FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2116431176> ?p ?o ?g. }

• W2116431176 endingPage "98" @default.
• W2116431176 startingPage "92" @default.
• W2116431176 abstract "Coacervation of soluble tropoelastin molecules is characterized by thermodynamically reversible association as temperature is increased under appropriately juxtaposed ionic conditions, protein concentration and pH. Coacervation plays a critical role in the assembly of these elastin precursors in elastic fiber formation. To examine the effect of physiological parameters on the ability of tropoelastin molecules to associate, solutions of recombinant human tropoelastin were monitored spectrophotometrically by light scattering over a broad range of temperatures. Coacervation of recombinant human tropoelastin is strongly influenced by the concentration of protein and NaCl and to a lesser extent on pH. Trends towards maximal association are apparent when each of these parameters is varied. Remarkably, optimal coacervation is found at 37°C, 150mM NaCl and pH7–8. Using the data generated by time courses, estimates of thermodynamic parameters were made. These estimates confirm that Coacervation is endothermic and is marked by a strong entropic contribution. Circular dichroism of recombinant human tropoelastin revealed that, rather than being random, the structure is compatible with being largely that, of an all-β protein (with secondary structure estimated to be 3%α-helix, 41%β-sheet, 21%β-turn and 33% other), exhibiting a spectrum as previously seen for tropoelastin populations and soluble elastin from naturally-derived sources." @default.
• W2116431176 created "2016-06-24" @default.
• W2116431176 creator A5007081664 @default.
• W2116431176 creator A5059290467 @default.
• W2116431176 creator A5062838605 @default.
• W2116431176 date "1997-11-15" @default.
• W2116431176 modified "2023-10-16" @default.
• W2116431176 title "Coacervation Characteristics of Recombinant Human Tropoelastin" @default.
• W2116431176 cites W1161366472 @default.
• W2116431176 cites W1504680742 @default.
• W2116431176 cites W1602506920 @default.
• W2116431176 cites W1619895170 @default.
• W2116431176 cites W1641205561 @default.
• W2116431176 cites W1852754054 @default.
• W2116431176 cites W1970147513 @default.
• W2116431176 cites W1976175443 @default.
• W2116431176 cites W1999347645 @default.
• W2116431176 cites W2001220175 @default.
• W2116431176 cites W2006791133 @default.
• W2116431176 cites W2009825302 @default.
• W2116431176 cites W2013302352 @default.
• W2116431176 cites W2015127183 @default.
• W2116431176 cites W2015278241 @default.
• W2116431176 cites W2017276607 @default.
• W2116431176 cites W2017690228 @default.
• W2116431176 cites W2023021766 @default.
• W2116431176 cites W2023527051 @default.
• W2116431176 cites W2030383861 @default.
• W2116431176 cites W2030951479 @default.
• W2116431176 cites W2044053791 @default.
• W2116431176 cites W2057609017 @default.
• W2116431176 cites W2065471983 @default.
• W2116431176 cites W2066784792 @default.
• W2116431176 cites W2067758677 @default.
• W2116431176 cites W2075990016 @default.
• W2116431176 cites W2077896437 @default.
• W2116431176 cites W2079302082 @default.
• W2116431176 cites W2114155418 @default.
• W2116431176 cites W2215153916 @default.
• W2116431176 cites W2226003216 @default.
• W2116431176 cites W2413667954 @default.
• W2116431176 cites W973302723 @default.
• W2116431176 doi "https://doi.org/10.1111/j.1432-1033.1997.00092.x" @default.
• W2116431176 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9431995" @default.
• W2116431176 hasPublicationYear "1997" @default.
• W2116431176 type Work @default.
• W2116431176 sameAs 2116431176 @default.
• W2116431176 citedByCount "215" @default.
• W2116431176 countsByYear W21164311762012 @default.
• W2116431176 countsByYear W21164311762013 @default.
• W2116431176 countsByYear W21164311762014 @default.
• W2116431176 countsByYear W21164311762015 @default.
• W2116431176 countsByYear W21164311762016 @default.
• W2116431176 countsByYear W21164311762017 @default.
• W2116431176 countsByYear W21164311762018 @default.
• W2116431176 countsByYear W21164311762019 @default.
• W2116431176 countsByYear W21164311762020 @default.
• W2116431176 countsByYear W21164311762021 @default.
• W2116431176 countsByYear W21164311762022 @default.
• W2116431176 countsByYear W21164311762023 @default.
• W2116431176 crossrefType "journal-article" @default.
• W2116431176 hasAuthorship W2116431176A5007081664 @default.
• W2116431176 hasAuthorship W2116431176A5059290467 @default.
• W2116431176 hasAuthorship W2116431176A5062838605 @default.
• W2116431176 hasConcept C104317684 @default.
• W2116431176 hasConcept C12554922 @default.
• W2116431176 hasConcept C133571119 @default.
• W2116431176 hasConcept C185592680 @default.
• W2116431176 hasConcept C2779869378 @default.
• W2116431176 hasConcept C2780299668 @default.
• W2116431176 hasConcept C40767141 @default.
• W2116431176 hasConcept C54355233 @default.
• W2116431176 hasConcept C55493867 @default.
• W2116431176 hasConcept C8010536 @default.
• W2116431176 hasConcept C83029808 @default.
• W2116431176 hasConcept C86803240 @default.
• W2116431176 hasConceptScore W2116431176C104317684 @default.
• W2116431176 hasConceptScore W2116431176C12554922 @default.
• W2116431176 hasConceptScore W2116431176C133571119 @default.
• W2116431176 hasConceptScore W2116431176C185592680 @default.
• W2116431176 hasConceptScore W2116431176C2779869378 @default.
• W2116431176 hasConceptScore W2116431176C2780299668 @default.
• W2116431176 hasConceptScore W2116431176C40767141 @default.
• W2116431176 hasConceptScore W2116431176C54355233 @default.
• W2116431176 hasConceptScore W2116431176C55493867 @default.
• W2116431176 hasConceptScore W2116431176C8010536 @default.
• W2116431176 hasConceptScore W2116431176C83029808 @default.
• W2116431176 hasConceptScore W2116431176C86803240 @default.
• W2116431176 hasIssue "1" @default.
• W2116431176 hasLocation W21164311761 @default.
• W2116431176 hasLocation W21164311762 @default.
• W2116431176 hasOpenAccess W2116431176 @default.
• W2116431176 hasPrimaryLocation W21164311761 @default.
• W2116431176 hasRelatedWork W1764979870 @default.
• W2116431176 hasRelatedWork W1771594097 @default.
• W2116431176 hasRelatedWork W1969749903 @default.
• W2116431176 hasRelatedWork W2047733245 @default.
• W2116431176 hasRelatedWork W2066186775 @default.

• next