FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2116465729> ?p ?o ?g. }

• W2116465729 endingPage "e7196" @default.
• W2116465729 startingPage "e7196" @default.
• W2116465729 abstract "We hypothesized that the percent adherence to antiretroviral therapy necessary to maintain HIV suppression would decrease with longer duration of viral suppression.Eligible participants were identified from the REACH cohort of marginally housed HIV infected adults in San Francisco. Adherence to antiretroviral therapy was measured through pill counts obtained at unannounced visits by research staff to each participant's usual place of residence. Marginal structural models and targeted maximum likelihood estimation methodologies were used to determine the effect of adherence to antiretroviral therapy on the probability of virologic failure during early and late viral suppression.A total of 221 subjects were studied (median age 44.1 years; median CD4+ T cell nadir 206 cells/mm(3)). Most subjects were taking the following types of antiretroviral regimens: non-nucleoside reverse transcriptase inhibitor based (37%), ritonavir boosted protease inhibitor based (28%), or unboosted protease inhibitor based (25%). Comparing the probability of failure just after achieving suppression vs. after 12 consecutive months of suppression, there was a statistically significant decrease in the probability of virologic failure for each range of adherence proportions we considered, as long as adherence was greater than 50%. The estimated risk difference, comparing the probability of virologic failure after 1 month vs. after 12 months of continuous viral suppression was 0.47 (95% CI 0.23-0.63) at 50-74% adherence, 0.29 (CI 0.03-0.50) at 75-89% adherence, and 0.36 (CI 0.23-0.48) at 90-100% adherence.The risk of virologic failure for adherence greater than 50% declines with longer duration of continuous suppression. While high adherence is required to maximize the probability of durable viral suppression, the range of adherence capable of sustaining viral suppression is wider after prolonged periods of viral suppression." @default.
• W2116465729 created "2016-06-24" @default.
• W2116465729 creator A5012143724 @default.
• W2116465729 creator A5055204699 @default.
• W2116465729 creator A5063704053 @default.
• W2116465729 creator A5073389592 @default.
• W2116465729 date "2009-09-29" @default.
• W2116465729 modified "2023-10-06" @default.
• W2116465729 title "The Risk of Virologic Failure Decreases with Duration of HIV Suppression, at Greater than 50% Adherence to Antiretroviral Therapy" @default.
• W2116465729 cites W1964020548 @default.
• W2116465729 cites W1973708179 @default.
• W2116465729 cites W1978540833 @default.
• W2116465729 cites W1982612158 @default.
• W2116465729 cites W1985429455 @default.
• W2116465729 cites W1990788636 @default.
• W2116465729 cites W1995127770 @default.
• W2116465729 cites W1997491132 @default.
• W2116465729 cites W2007607803 @default.
• W2116465729 cites W2008989084 @default.
• W2116465729 cites W2014005798 @default.
• W2116465729 cites W2022450888 @default.
• W2116465729 cites W2037635462 @default.
• W2116465729 cites W2048689803 @default.
• W2116465729 cites W2051269276 @default.
• W2116465729 cites W2071066672 @default.
• W2116465729 cites W2075155298 @default.
• W2116465729 cites W2082299845 @default.
• W2116465729 cites W2087309699 @default.
• W2116465729 cites W2101516953 @default.
• W2116465729 cites W2107228938 @default.
• W2116465729 cites W2110819064 @default.
• W2116465729 cites W2116926841 @default.
• W2116465729 cites W2121731508 @default.
• W2116465729 cites W2147662860 @default.
• W2116465729 cites W2160676835 @default.
• W2116465729 cites W2164099498 @default.
• W2116465729 cites W2165367950 @default.
• W2116465729 cites W2166653928 @default.
• W2116465729 cites W2167310701 @default.
• W2116465729 cites W2167877735 @default.
• W2116465729 cites W2171196763 @default.
• W2116465729 cites W2337376130 @default.
• W2116465729 cites W3106889297 @default.
• W2116465729 cites W99771653 @default.
• W2116465729 doi "https://doi.org/10.1371/journal.pone.0007196" @default.
• W2116465729 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2747009" @default.
• W2116465729 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19787058" @default.
• W2116465729 hasPublicationYear "2009" @default.
• W2116465729 type Work @default.
• W2116465729 sameAs 2116465729 @default.
• W2116465729 citedByCount "112" @default.
• W2116465729 countsByYear W21164657292012 @default.
• W2116465729 countsByYear W21164657292013 @default.
• W2116465729 countsByYear W21164657292014 @default.
• W2116465729 countsByYear W21164657292015 @default.
• W2116465729 countsByYear W21164657292016 @default.
• W2116465729 countsByYear W21164657292017 @default.
• W2116465729 countsByYear W21164657292018 @default.
• W2116465729 countsByYear W21164657292019 @default.
• W2116465729 countsByYear W21164657292020 @default.
• W2116465729 countsByYear W21164657292021 @default.
• W2116465729 countsByYear W21164657292022 @default.
• W2116465729 countsByYear W21164657292023 @default.
• W2116465729 crossrefType "journal-article" @default.
• W2116465729 hasAuthorship W2116465729A5012143724 @default.
• W2116465729 hasAuthorship W2116465729A5055204699 @default.
• W2116465729 hasAuthorship W2116465729A5063704053 @default.
• W2116465729 hasAuthorship W2116465729A5073389592 @default.
• W2116465729 hasBestOaLocation W21164657291 @default.
• W2116465729 hasConcept C126322002 @default.
• W2116465729 hasConcept C142462285 @default.
• W2116465729 hasConcept C201903717 @default.
• W2116465729 hasConcept C203014093 @default.
• W2116465729 hasConcept C2779298103 @default.
• W2116465729 hasConcept C2781143361 @default.
• W2116465729 hasConcept C2993143319 @default.
• W2116465729 hasConcept C3013748606 @default.
• W2116465729 hasConcept C71924100 @default.
• W2116465729 hasConcept C72563966 @default.
• W2116465729 hasConceptScore W2116465729C126322002 @default.
• W2116465729 hasConceptScore W2116465729C142462285 @default.
• W2116465729 hasConceptScore W2116465729C201903717 @default.
• W2116465729 hasConceptScore W2116465729C203014093 @default.
• W2116465729 hasConceptScore W2116465729C2779298103 @default.
• W2116465729 hasConceptScore W2116465729C2781143361 @default.
• W2116465729 hasConceptScore W2116465729C2993143319 @default.
• W2116465729 hasConceptScore W2116465729C3013748606 @default.
• W2116465729 hasConceptScore W2116465729C71924100 @default.
• W2116465729 hasConceptScore W2116465729C72563966 @default.
• W2116465729 hasIssue "9" @default.
• W2116465729 hasLocation W21164657291 @default.
• W2116465729 hasLocation W21164657292 @default.
• W2116465729 hasLocation W21164657293 @default.
• W2116465729 hasLocation W21164657294 @default.
• W2116465729 hasLocation W21164657295 @default.
• W2116465729 hasLocation W21164657296 @default.
• W2116465729 hasLocation W21164657297 @default.
• W2116465729 hasOpenAccess W2116465729 @default.

• next