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- W2116467413 abstract "The Universal PBM Resource for Oligonucleotide Binding Evaluation (UniPROBE) serves as a convenient source of information on published data generated using universal protein-binding microarray (PBM) technology, which provides in vitro data about the relative DNA-binding preferences of transcription factors for all possible sequence variants of a length k (‘k-mers’). The database displays important information about the proteins and displays their DNA-binding specificity data in terms of k-mers, position weight matrices and graphical sequence logos. This update to the database documents the growth of UniPROBE since the last update 4 years ago, and introduces a variety of new features and tools, including a new streamlined pipeline that facilitates data deposition by universal PBM data generators in the research community, a tool that generates putative nonbinding (i.e. negative control) DNA sequences for one or more proteins and novel motifs obtained by analyzing the PBM data using the BEEML-PBM algorithm for motif inference. The UniPROBE database is available at http://uniprobe.org." @default.
- W2116467413 created "2016-06-24" @default.
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- W2116467413 date "2014-11-05" @default.
- W2116467413 modified "2023-10-12" @default.
- W2116467413 title "UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein–DNA interactions" @default.
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- W2116467413 doi "https://doi.org/10.1093/nar/gku1045" @default.
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