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• W2116502195 abstract "We measure optical absorption in color-producing enzymatic reactions for biochemical analysis with a microscale optofluidic device. Cavity-enhanced laser spectrophotometry is performed on analytes within a microfluidic channel at visible wavelengths with silicon nitride microring resonators of 100 µm radius and quality factor of ~180,000. The resonator transmission spectrum is analyzed to determine optical absorption with a detection limit of 0.12 cm(-1). The device can be used to detect the activity of individual enzymes in a few minutes within a 100 fL sensing volume. The high sensitivity, small footprint, and low analyte consumption make absorption-based microring resonators attractive for lab-on-a-chip applications." @default.
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• W2116502195 date "2011-01-05" @default.
• W2116502195 modified "2023-10-17" @default.
• W2116502195 title "On-chip spectrophotometry for bioanalysis using microring resonators" @default.
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• W2116502195 doi "https://doi.org/10.1364/boe.2.000271" @default.
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