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- W2116558178 abstract "Background: Doppler Myokardial Imaging (DMI) has been shown to differentiate myocardial hypertrophy induced by aortic ligation and exercise in animal models. The purpose of this clinical study was to compare the impact of aortic stenosis and arterial hypertension on DMI parameters of regional left ventricular function. Methods: Twenty patients with arterial hypertension (HTN) and twenty patients with aortic stenosis (AOS) and exclusion of arterial hypertension were enrolled in the study. Coronary artery disease was ruled out by coronary angiography and LV angiography was done to measure ejection fraction in both groups. Ten age matched normals served as control. All patients had a conventional echocardiography study including a DMI study with an evaluation of the posterior wall derived from parasternal long axis views. The following parameters were assessed: enddiastolic wall thickness (WTed), peak systolic velocity (pVel), peak systolic strain rate (pSR), LV enddiastolic diameter (LVEDD) and LV ejection fraction (EF). Results: Both patient groups showed a normal EF and there was no difference in WTed. Peak velocity in the AOS group (aortic orifice area 0.6 ± 0.2 cm 2 )w as significantly lower compared to normals but did not differ from the HTN group. In contrast peak strain rate in the AOS group was significantly lower compared to both the HTN group and the normals (see table)." @default.
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- W2116558178 date "2003-12-01" @default.
- W2116558178 modified "2023-09-25" @default.
- W2116558178 title "506 Doppler myocardial imaging differentiates myocardial hypertrophy induced either by arterial hypertension or aortic stenosis" @default.
- W2116558178 doi "https://doi.org/10.1016/s1525-2167(03)90788-8" @default.
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