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• W2116562478 startingPage "1667" @default.
• W2116562478 abstract "In this paper, a DNA–PEI microcapsule with novel nuclease-responsive controlled release properties was demonstrated. This microcapsule was constructed by the self-assembly of native DNA and PEI, and can work as a dual carrier for both DNA in the capsule shell and drugs inside the capsule. The controlled release behavior of the model drug BSA–FITC was studied using fluorescence microscopy and UV spectroscopy, and the results show that the synergetic controlled release can be triggered very well by a bio-stimulus, DNA nuclease recognition capsule decomposition, as well as the pH value and salt concentration. The therapeutic effects of the drug are enhanced due to the bio-stimuli responsive properties and the synergetic release of DNA and the drug together." @default.
• W2116562478 created "2016-06-24" @default.
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• W2116562478 date "2014-01-01" @default.
• W2116562478 modified "2023-10-01" @default.
• W2116562478 title "Nuclease-responsive DNA–PEI hollow microcapsules for bio-stimuli controlled release" @default.
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• W2116562478 doi "https://doi.org/10.1039/c3tb21191f" @default.
• W2116562478 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32261395" @default.
• W2116562478 hasPublicationYear "2014" @default.
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