Matches in SemOpenAlex for { <https://semopenalex.org/work/W2116701737> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2116701737 endingPage "397" @default.
- W2116701737 startingPage "391" @default.
- W2116701737 abstract "While the incidence of Clostridium difficile-associated diarrhoea (CDAD) has increased sharply over the last 15 years, its risk factors are still not well defined. The aim of this study was to review cases of CDAD at the major teaching hospital in Tasmania, Australia, to identify risk factors for CDAD and their association with prognosis.A retrospective review of the medical records of adult patients admitted to the hospital between January 1994 and December 1996 was performed. Sixty-four patients who developed CDAD prior to or during their admission, and an additional 120 diarrhoea-free patients (the control group) were studied. An extensive range of demographic and clinical variables were recorded, and the differences between the control group and patients with CDAD were evaluated.The CDAD patients had a median age of 66 years (range 22-95 years), with females accounting for 52% of cases. There were no significant demographic differences from the control group. Identifiable risk factors for developing CDAD were severe underlying disease, renal impairment, exposure to antibiotics or antineoplastic agents, and the use of total parenteral nutrition or nasogastric feeding. Cephalosporins were the most frequently used antibiotics in both CDAD and control patients, with cefotaxime being the only antibiotic which was identified as being significantly associated with an increased risk of CDAD. The median length of diarrhoea episodes was 9 days (range 1-60 days). The mortality rate was 17.2%, and factors associated with a poor prognosis were older age, severe underlying disease, renal impairment and failure to treat with metronidazole or vancomycin. Delay in starting specific treatment and use of codeine were related to prolonged CDAD.CDAD is a growing contributor to hospital morbidity and costs. Severely ill patients with compromised immune function are particularly susceptible, with antibiotic use being a major risk factor. Prompt diagnosis and initiation of treatment are important factors in the improvement of prognosis." @default.
- W2116701737 created "2016-06-24" @default.
- W2116701737 creator A5005077426 @default.
- W2116701737 creator A5005569743 @default.
- W2116701737 creator A5013829448 @default.
- W2116701737 creator A5073984194 @default.
- W2116701737 date "1997-10-01" @default.
- W2116701737 modified "2023-09-26" @default.
- W2116701737 title "Case-controlled review of Clostridium difficile-associated diarrhoea in Southern Tasmania" @default.
- W2116701737 cites W1964965696 @default.
- W2116701737 cites W1964983502 @default.
- W2116701737 cites W1966195600 @default.
- W2116701737 cites W1995198431 @default.
- W2116701737 cites W1999940957 @default.
- W2116701737 cites W2008853677 @default.
- W2116701737 cites W2033486769 @default.
- W2116701737 cites W2034312270 @default.
- W2116701737 cites W2049046504 @default.
- W2116701737 cites W2049898395 @default.
- W2116701737 cites W2050132609 @default.
- W2116701737 cites W2050737558 @default.
- W2116701737 cites W2064106468 @default.
- W2116701737 cites W2066446836 @default.
- W2116701737 cites W2070965258 @default.
- W2116701737 cites W2092235052 @default.
- W2116701737 cites W2094898264 @default.
- W2116701737 cites W2126927211 @default.
- W2116701737 cites W2128205055 @default.
- W2116701737 cites W2131938833 @default.
- W2116701737 cites W2318911370 @default.
- W2116701737 cites W2468347553 @default.
- W2116701737 doi "https://doi.org/10.1111/j.1365-2710.1997.tb00022.x" @default.
- W2116701737 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19160724" @default.
- W2116701737 hasPublicationYear "1997" @default.
- W2116701737 type Work @default.
- W2116701737 sameAs 2116701737 @default.
- W2116701737 citedByCount "9" @default.
- W2116701737 countsByYear W21167017372012 @default.
- W2116701737 countsByYear W21167017372014 @default.
- W2116701737 countsByYear W21167017372015 @default.
- W2116701737 crossrefType "journal-article" @default.
- W2116701737 hasAuthorship W2116701737A5005077426 @default.
- W2116701737 hasAuthorship W2116701737A5005569743 @default.
- W2116701737 hasAuthorship W2116701737A5013829448 @default.
- W2116701737 hasAuthorship W2116701737A5073984194 @default.
- W2116701737 hasBestOaLocation W21167017371 @default.
- W2116701737 hasConcept C120665830 @default.
- W2116701737 hasConcept C121332964 @default.
- W2116701737 hasConcept C126322002 @default.
- W2116701737 hasConcept C141071460 @default.
- W2116701737 hasConcept C167135981 @default.
- W2116701737 hasConcept C177713679 @default.
- W2116701737 hasConcept C187212893 @default.
- W2116701737 hasConcept C195910791 @default.
- W2116701737 hasConcept C2777396551 @default.
- W2116701737 hasConcept C2779802037 @default.
- W2116701737 hasConcept C2994496256 @default.
- W2116701737 hasConcept C501593827 @default.
- W2116701737 hasConcept C61511704 @default.
- W2116701737 hasConcept C71924100 @default.
- W2116701737 hasConcept C86803240 @default.
- W2116701737 hasConcept C89423630 @default.
- W2116701737 hasConceptScore W2116701737C120665830 @default.
- W2116701737 hasConceptScore W2116701737C121332964 @default.
- W2116701737 hasConceptScore W2116701737C126322002 @default.
- W2116701737 hasConceptScore W2116701737C141071460 @default.
- W2116701737 hasConceptScore W2116701737C167135981 @default.
- W2116701737 hasConceptScore W2116701737C177713679 @default.
- W2116701737 hasConceptScore W2116701737C187212893 @default.
- W2116701737 hasConceptScore W2116701737C195910791 @default.
- W2116701737 hasConceptScore W2116701737C2777396551 @default.
- W2116701737 hasConceptScore W2116701737C2779802037 @default.
- W2116701737 hasConceptScore W2116701737C2994496256 @default.
- W2116701737 hasConceptScore W2116701737C501593827 @default.
- W2116701737 hasConceptScore W2116701737C61511704 @default.
- W2116701737 hasConceptScore W2116701737C71924100 @default.
- W2116701737 hasConceptScore W2116701737C86803240 @default.
- W2116701737 hasConceptScore W2116701737C89423630 @default.
- W2116701737 hasIssue "5-6" @default.
- W2116701737 hasLocation W21167017371 @default.
- W2116701737 hasLocation W21167017372 @default.
- W2116701737 hasOpenAccess W2116701737 @default.
- W2116701737 hasPrimaryLocation W21167017371 @default.
- W2116701737 hasRelatedWork W1433265346 @default.
- W2116701737 hasRelatedWork W1990454964 @default.
- W2116701737 hasRelatedWork W2022692281 @default.
- W2116701737 hasRelatedWork W2054523769 @default.
- W2116701737 hasRelatedWork W207626099 @default.
- W2116701737 hasRelatedWork W2080249364 @default.
- W2116701737 hasRelatedWork W2119616599 @default.
- W2116701737 hasRelatedWork W2285745285 @default.
- W2116701737 hasRelatedWork W2769349951 @default.
- W2116701737 hasRelatedWork W2513322366 @default.
- W2116701737 hasVolume "22" @default.
- W2116701737 isParatext "false" @default.
- W2116701737 isRetracted "false" @default.
- W2116701737 magId "2116701737" @default.
- W2116701737 workType "article" @default.