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- W2116710052 abstract "To estimate futile cycles in the metabolism of glucose in liver, rat hepatocytes were incubated with glucose labelled with tritium in position 2 and 5 and uniformly with 14C. The yield in water from 2-3H glucose was 1.5 times that from 5-3H glucose and 2 to 3 times that of 14C utilization. Lactate addition had little effect on the water yield from 2-3H glucose but depressed that from 5-3H glucose and utilization of 14C. Our results indicate the occurrence of futile cycles glucose → glucose-6P → glucose and fructose-6P → fructose 1,6diP → fructose-6P in rat liver. An estimate of recycling at the glucose-6P level is presented." @default.
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- W2116710052 date "1973-10-01" @default.
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- W2116710052 title "Isotopic evidence for futile cycles in liver cells" @default.
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- W2116710052 doi "https://doi.org/10.1016/0006-291x(73)90811-5" @default.
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