FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2116719557> ?p ?o ?g. }

• W2116719557 endingPage "356" @default.
• W2116719557 startingPage "351" @default.
• W2116719557 abstract "The crystal structure of the kinase domain from human checkpoint kinase 2 (Chk2) has shown, for the first time, the reciprocal exchange of activation segments between two adjacent molecules and provides the molecular basis for understanding the observed mode of Chk2 kinase activation via trans-autophosphorylation. With further examples of activation segment exchanged kinase domains now publicly available (i.e. Ste20-like kinase, Ser/Thr kinase 10 and Death-associated protein kinase 3), we suggest that this phenomenon represents a common mechanism of activation amongst a particular subset of protein kinases, that is, those that are dimeric (either transiently or constitutively), that undergo activation by autophosphorylation and that have activation segment amino acid sequences that do not resemble those of their substrate consensus sequence." @default.
• W2116719557 created "2016-06-24" @default.
• W2116719557 creator A5011271805 @default.
• W2116719557 creator A5013336817 @default.
• W2116719557 creator A5090085169 @default.
• W2116719557 date "2007-08-01" @default.
• W2116719557 modified "2023-10-16" @default.
• W2116719557 title "Activation segment exchange: a common mechanism of kinase autophosphorylation?" @default.
• W2116719557 cites W1788133348 @default.
• W2116719557 cites W1978218402 @default.
• W2116719557 cites W1981658281 @default.
• W2116719557 cites W1987190589 @default.
• W2116719557 cites W2018078080 @default.
• W2116719557 cites W2019392060 @default.
• W2116719557 cites W2021526208 @default.
• W2116719557 cites W2030205108 @default.
• W2116719557 cites W2036786051 @default.
• W2116719557 cites W2057069307 @default.
• W2116719557 cites W2068435780 @default.
• W2116719557 cites W2075352286 @default.
• W2116719557 cites W2079867322 @default.
• W2116719557 cites W2098416804 @default.
• W2116719557 cites W2117355601 @default.
• W2116719557 cites W2125433806 @default.
• W2116719557 cites W2129004089 @default.
• W2116719557 cites W2129353954 @default.
• W2116719557 cites W2147891181 @default.
• W2116719557 cites W2152696380 @default.
• W2116719557 cites W2171128065 @default.
• W2116719557 cites W4385126812 @default.
• W2116719557 doi "https://doi.org/10.1016/j.tibs.2007.06.004" @default.
• W2116719557 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17627826" @default.
• W2116719557 hasPublicationYear "2007" @default.
• W2116719557 type Work @default.
• W2116719557 sameAs 2116719557 @default.
• W2116719557 citedByCount "87" @default.
• W2116719557 countsByYear W21167195572012 @default.
• W2116719557 countsByYear W21167195572013 @default.
• W2116719557 countsByYear W21167195572014 @default.
• W2116719557 countsByYear W21167195572015 @default.
• W2116719557 countsByYear W21167195572016 @default.
• W2116719557 countsByYear W21167195572017 @default.
• W2116719557 countsByYear W21167195572019 @default.
• W2116719557 countsByYear W21167195572020 @default.
• W2116719557 countsByYear W21167195572021 @default.
• W2116719557 countsByYear W21167195572022 @default.
• W2116719557 countsByYear W21167195572023 @default.
• W2116719557 crossrefType "journal-article" @default.
• W2116719557 hasAuthorship W2116719557A5011271805 @default.
• W2116719557 hasAuthorship W2116719557A5013336817 @default.
• W2116719557 hasAuthorship W2116719557A5090085169 @default.
• W2116719557 hasConcept C104317684 @default.
• W2116719557 hasConcept C124160383 @default.
• W2116719557 hasConcept C137361374 @default.
• W2116719557 hasConcept C143065580 @default.
• W2116719557 hasConcept C150109051 @default.
• W2116719557 hasConcept C159479382 @default.
• W2116719557 hasConcept C184235292 @default.
• W2116719557 hasConcept C185592680 @default.
• W2116719557 hasConcept C32619005 @default.
• W2116719557 hasConcept C55493867 @default.
• W2116719557 hasConcept C59143045 @default.
• W2116719557 hasConcept C82495950 @default.
• W2116719557 hasConcept C86803240 @default.
• W2116719557 hasConcept C90934575 @default.
• W2116719557 hasConcept C95444343 @default.
• W2116719557 hasConcept C97029542 @default.
• W2116719557 hasConcept C99405784 @default.
• W2116719557 hasConceptScore W2116719557C104317684 @default.
• W2116719557 hasConceptScore W2116719557C124160383 @default.
• W2116719557 hasConceptScore W2116719557C137361374 @default.
• W2116719557 hasConceptScore W2116719557C143065580 @default.
• W2116719557 hasConceptScore W2116719557C150109051 @default.
• W2116719557 hasConceptScore W2116719557C159479382 @default.
• W2116719557 hasConceptScore W2116719557C184235292 @default.
• W2116719557 hasConceptScore W2116719557C185592680 @default.
• W2116719557 hasConceptScore W2116719557C32619005 @default.
• W2116719557 hasConceptScore W2116719557C55493867 @default.
• W2116719557 hasConceptScore W2116719557C59143045 @default.
• W2116719557 hasConceptScore W2116719557C82495950 @default.
• W2116719557 hasConceptScore W2116719557C86803240 @default.
• W2116719557 hasConceptScore W2116719557C90934575 @default.
• W2116719557 hasConceptScore W2116719557C95444343 @default.
• W2116719557 hasConceptScore W2116719557C97029542 @default.
• W2116719557 hasConceptScore W2116719557C99405784 @default.
• W2116719557 hasIssue "8" @default.
• W2116719557 hasLocation W21167195571 @default.
• W2116719557 hasLocation W21167195572 @default.
• W2116719557 hasOpenAccess W2116719557 @default.
• W2116719557 hasPrimaryLocation W21167195571 @default.
• W2116719557 hasRelatedWork W1983481482 @default.
• W2116719557 hasRelatedWork W1999628035 @default.
• W2116719557 hasRelatedWork W2031154171 @default.
• W2116719557 hasRelatedWork W2033421786 @default.
• W2116719557 hasRelatedWork W2053685014 @default.
• W2116719557 hasRelatedWork W2064943475 @default.
• W2116719557 hasRelatedWork W2122407726 @default.
• W2116719557 hasRelatedWork W2145966802 @default.

• next