FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2116723621> ?p ?o ?g. }

• W2116723621 endingPage "1746" @default.
• W2116723621 startingPage "1736" @default.
• W2116723621 abstract "Intensity-modulated radiation therapy can be conveniently delivered with a multileaf collimator. With this method, the entire field is not delivered at once, but rather it is composed of many subfields defined by the leaf positions as a function of beam on time. At any given instant, only these subfields are delivered. During treatment, if the organ moves, part of the volume may move in or out of these subfields. Due to this interplay between organ motion and leaf motion the delivered dose may be different from what was planned. In this work, we present a method that calculates the effects of organ motion on delivered dose. The direction of organ motion may be parallel or perpendicular to the leaf motion, and the effect can be calculated for a single fraction or for multiple fractions. Three breast patients and four lung patients were included in this study,with the amplitude of the organ motion varying from +/- 3.5 mm to +/- 10 mm, and the period varying from 4 to 8 seconds. Calculations were made for these patients with and without organ motion, and results were examined in terms of isodose distribution and dose volume histograms. Each calculation was repeated ten times in order to estimate the statistical uncertainties. For selected patients, calculations were also made with conventional treatment technique. The effects of organ motion on conventional techniques were compared relative to that on IMRT techniques. For breast treatment, the effect of organ motion primarily broadened the penumbra at the posterior field edge. The dose in the rest of the treatment volume was not significantly affected. For lung treatment, the effect also broadened the penumbra and degraded the coverage of the planning target volume (PTV). However, the coverage of the clinical target volume (CTV) was not much affected, provided the PTV margin was adequate. The same effects were observed for both IMRT and conventional treatment techniques. For the IMRT technique, the standard deviations of ten samples of a 30-fraction calculation were very small for all patients, implying that over a typical treatment course of 30 fractions, the delivered dose was very close to the expected value. Hence, under typical clinical conditions, the effect of organ motion on delivered dose can be calculated without considering the interplay between the organ motion and the leaf motion. It can be calculated as the weighted average of the dose distribution without organ motion with the distribution of organ motion. Since the effects of organ motion on dose were comparable for both IMRT and conventional techniques, the PTV margin should remain the same for both techniques." @default.
• W2116723621 created "2016-06-24" @default.
• W2116723621 creator A5043964591 @default.
• W2116723621 creator A5059651661 @default.
• W2116723621 creator A5082845902 @default.
• W2116723621 date "2003-06-25" @default.
• W2116723621 modified "2023-10-18" @default.
• W2116723621 title "The effects of intra-fraction organ motion on the delivery of intensity-modulated field with a multileaf collimator" @default.
• W2116723621 cites W1969102615 @default.
• W2116723621 cites W1973073129 @default.
• W2116723621 cites W1981598225 @default.
• W2116723621 cites W1998225682 @default.
• W2116723621 cites W1998759803 @default.
• W2116723621 cites W2007256049 @default.
• W2116723621 cites W2014189016 @default.
• W2116723621 cites W2023670264 @default.
• W2116723621 cites W2027226834 @default.
• W2116723621 cites W2041332468 @default.
• W2116723621 cites W2044788192 @default.
• W2116723621 cites W2045260373 @default.
• W2116723621 cites W2057655643 @default.
• W2116723621 cites W2075859882 @default.
• W2116723621 cites W2093374013 @default.
• W2116723621 cites W2121562131 @default.
• W2116723621 cites W2144644621 @default.
• W2116723621 cites W2147544224 @default.
• W2116723621 cites W2163827108 @default.
• W2116723621 cites W2167767036 @default.
• W2116723621 doi "https://doi.org/10.1118/1.1578771" @default.
• W2116723621 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12906191" @default.
• W2116723621 hasPublicationYear "2003" @default.
• W2116723621 type Work @default.
• W2116723621 sameAs 2116723621 @default.
• W2116723621 citedByCount "148" @default.
• W2116723621 countsByYear W21167236212012 @default.
• W2116723621 countsByYear W21167236212013 @default.
• W2116723621 countsByYear W21167236212014 @default.
• W2116723621 countsByYear W21167236212015 @default.
• W2116723621 countsByYear W21167236212016 @default.
• W2116723621 countsByYear W21167236212017 @default.
• W2116723621 countsByYear W21167236212018 @default.
• W2116723621 countsByYear W21167236212019 @default.
• W2116723621 countsByYear W21167236212020 @default.
• W2116723621 countsByYear W21167236212021 @default.
• W2116723621 countsByYear W21167236212022 @default.
• W2116723621 countsByYear W21167236212023 @default.
• W2116723621 crossrefType "journal-article" @default.
• W2116723621 hasAuthorship W2116723621A5043964591 @default.
• W2116723621 hasAuthorship W2116723621A5059651661 @default.
• W2116723621 hasAuthorship W2116723621A5082845902 @default.
• W2116723621 hasConcept C120665830 @default.
• W2116723621 hasConcept C121332964 @default.
• W2116723621 hasConcept C126838900 @default.
• W2116723621 hasConcept C161471255 @default.
• W2116723621 hasConcept C201645570 @default.
• W2116723621 hasConcept C2779200277 @default.
• W2116723621 hasConcept C2989005 @default.
• W2116723621 hasConcept C48925448 @default.
• W2116723621 hasConcept C509974204 @default.
• W2116723621 hasConcept C71924100 @default.
• W2116723621 hasConcept C75088862 @default.
• W2116723621 hasConcept C89631360 @default.
• W2116723621 hasConcept C96834759 @default.
• W2116723621 hasConceptScore W2116723621C120665830 @default.
• W2116723621 hasConceptScore W2116723621C121332964 @default.
• W2116723621 hasConceptScore W2116723621C126838900 @default.
• W2116723621 hasConceptScore W2116723621C161471255 @default.
• W2116723621 hasConceptScore W2116723621C201645570 @default.
• W2116723621 hasConceptScore W2116723621C2779200277 @default.
• W2116723621 hasConceptScore W2116723621C2989005 @default.
• W2116723621 hasConceptScore W2116723621C48925448 @default.
• W2116723621 hasConceptScore W2116723621C509974204 @default.
• W2116723621 hasConceptScore W2116723621C71924100 @default.
• W2116723621 hasConceptScore W2116723621C75088862 @default.
• W2116723621 hasConceptScore W2116723621C89631360 @default.
• W2116723621 hasConceptScore W2116723621C96834759 @default.
• W2116723621 hasIssue "7" @default.
• W2116723621 hasLocation W21167236211 @default.
• W2116723621 hasLocation W21167236212 @default.
• W2116723621 hasOpenAccess W2116723621 @default.
• W2116723621 hasPrimaryLocation W21167236211 @default.
• W2116723621 hasRelatedWork W1973741373 @default.
• W2116723621 hasRelatedWork W2015078496 @default.
• W2116723621 hasRelatedWork W2034399309 @default.
• W2116723621 hasRelatedWork W2051932757 @default.
• W2116723621 hasRelatedWork W2076772686 @default.
• W2116723621 hasRelatedWork W2394478904 @default.
• W2116723621 hasRelatedWork W2559601361 @default.
• W2116723621 hasRelatedWork W2951691405 @default.
• W2116723621 hasRelatedWork W3030937579 @default.
• W2116723621 hasRelatedWork W2061718935 @default.
• W2116723621 hasVolume "30" @default.
• W2116723621 isParatext "false" @default.
• W2116723621 isRetracted "false" @default.
• W2116723621 magId "2116723621" @default.
• W2116723621 workType "article" @default.