FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2116728057> ?p ?o ?g. }

• W2116728057 endingPage "1134" @default.
• W2116728057 startingPage "1124" @default.
• W2116728057 abstract "Rofecoxib, a cyclooxygenase 2 inhibitor (sometimes known as a specific cyclooxygenase 2 inhibitor or Coxib), is used in osteoarthritis (OA). Published information indicates rofecoxib's improved gastrointestinal safety profile over nonselective nonsteroidal anti-inflammatory agents (NSAIDs).To evaluate the efficacy and safety of rofecoxib in treating OA in 2 studies.Two randomized, double-blind, parallel-group studies in patients with OA of the knee or hip were conducted using identical entry criteria and end points. A 6-week placebo-controlled trial in 736 patients compared 12.5 and 25 mg of rofecoxib once daily with 800 mg of ibuprofen 3 times daily, and a 1-year study compared 12.5 and 25 mg of rofecoxib once daily with 50 mg of diclofenac 3 times daily in 693 patients.Rofecoxib, at 12.5 and 25 mg, demonstrated efficacy clinically comparable with ibuprofen, assessed by 3 primary end points according to predefined comparability criteria. Both rofecoxib doses and ibuprofen provided significantly greater efficacy than placebo on all primary end points at 6 weeks. Both rofecoxib doses and diclofenac showed similar efficacy over 1 year. All treatments were well tolerated.Rofecoxib is effective in treating OA with once-daily dosing for 6 weeks and 1 year. Rofecoxib was generally safe and well-tolerated in OA patients for 6 weeks and 1 year. Arch Fam Med. 2000;9:1124-1134" @default.
• W2116728057 created "2016-06-24" @default.
• W2116728057 creator A5015406504 @default.
• W2116728057 creator A5032780756 @default.
• W2116728057 creator A5040557381 @default.
• W2116728057 creator A5046382845 @default.
• W2116728057 creator A5057595655 @default.
• W2116728057 creator A5057877703 @default.
• W2116728057 creator A5059955758 @default.
• W2116728057 creator A5082331195 @default.
• W2116728057 date "2000-11-01" @default.
• W2116728057 modified "2023-10-14" @default.
• W2116728057 title "Rofecoxib, a New Cyclooxygenase 2 Inhibitor, Shows Sustained Efficacy, Comparable With Other Nonsteroidal Anti-inflammatory Drugs: A 6-Week and a 1-Year Trial in Patients With Osteoarthritis" @default.
• W2116728057 cites W130978029 @default.
• W2116728057 cites W180727785 @default.
• W2116728057 cites W191618243 @default.
• W2116728057 cites W2044750065 @default.
• W2116728057 cites W2048567767 @default.
• W2116728057 cites W2058147305 @default.
• W2116728057 cites W2081734937 @default.
• W2116728057 cites W2102272680 @default.
• W2116728057 cites W2105318758 @default.
• W2116728057 cites W2138698403 @default.
• W2116728057 cites W2147735977 @default.
• W2116728057 cites W2165276815 @default.
• W2116728057 cites W2266185506 @default.
• W2116728057 cites W2334931546 @default.
• W2116728057 cites W2341527569 @default.
• W2116728057 cites W2412481048 @default.
• W2116728057 cites W2415100273 @default.
• W2116728057 cites W2474526349 @default.
• W2116728057 cites W3204529085 @default.
• W2116728057 doi "https://doi.org/10.1001/archfami.9.10.1124" @default.
• W2116728057 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11115219" @default.
• W2116728057 hasPublicationYear "2000" @default.
• W2116728057 type Work @default.
• W2116728057 sameAs 2116728057 @default.
• W2116728057 citedByCount "111" @default.
• W2116728057 countsByYear W21167280572012 @default.
• W2116728057 countsByYear W21167280572014 @default.
• W2116728057 countsByYear W21167280572015 @default.
• W2116728057 countsByYear W21167280572016 @default.
• W2116728057 countsByYear W21167280572017 @default.
• W2116728057 countsByYear W21167280572018 @default.
• W2116728057 countsByYear W21167280572019 @default.
• W2116728057 crossrefType "journal-article" @default.
• W2116728057 hasAuthorship W2116728057A5015406504 @default.
• W2116728057 hasAuthorship W2116728057A5032780756 @default.
• W2116728057 hasAuthorship W2116728057A5040557381 @default.
• W2116728057 hasAuthorship W2116728057A5046382845 @default.
• W2116728057 hasAuthorship W2116728057A5057595655 @default.
• W2116728057 hasAuthorship W2116728057A5057877703 @default.
• W2116728057 hasAuthorship W2116728057A5059955758 @default.
• W2116728057 hasAuthorship W2116728057A5082331195 @default.
• W2116728057 hasConcept C126322002 @default.
• W2116728057 hasConcept C142724271 @default.
• W2116728057 hasConcept C181199279 @default.
• W2116728057 hasConcept C185592680 @default.
• W2116728057 hasConcept C204787440 @default.
• W2116728057 hasConcept C27081682 @default.
• W2116728057 hasConcept C2776164576 @default.
• W2116728057 hasConcept C2777288759 @default.
• W2116728057 hasConcept C2778582115 @default.
• W2116728057 hasConcept C2779689624 @default.
• W2116728057 hasConcept C2779826273 @default.
• W2116728057 hasConcept C2779944601 @default.
• W2116728057 hasConcept C42219234 @default.
• W2116728057 hasConcept C55493867 @default.
• W2116728057 hasConcept C71924100 @default.
• W2116728057 hasConcept C98274493 @default.
• W2116728057 hasConceptScore W2116728057C126322002 @default.
• W2116728057 hasConceptScore W2116728057C142724271 @default.
• W2116728057 hasConceptScore W2116728057C181199279 @default.
• W2116728057 hasConceptScore W2116728057C185592680 @default.
• W2116728057 hasConceptScore W2116728057C204787440 @default.
• W2116728057 hasConceptScore W2116728057C27081682 @default.
• W2116728057 hasConceptScore W2116728057C2776164576 @default.
• W2116728057 hasConceptScore W2116728057C2777288759 @default.
• W2116728057 hasConceptScore W2116728057C2778582115 @default.
• W2116728057 hasConceptScore W2116728057C2779689624 @default.
• W2116728057 hasConceptScore W2116728057C2779826273 @default.
• W2116728057 hasConceptScore W2116728057C2779944601 @default.
• W2116728057 hasConceptScore W2116728057C42219234 @default.
• W2116728057 hasConceptScore W2116728057C55493867 @default.
• W2116728057 hasConceptScore W2116728057C71924100 @default.
• W2116728057 hasConceptScore W2116728057C98274493 @default.
• W2116728057 hasIssue "10" @default.
• W2116728057 hasLocation W21167280571 @default.
• W2116728057 hasLocation W21167280572 @default.
• W2116728057 hasOpenAccess W2116728057 @default.
• W2116728057 hasPrimaryLocation W21167280571 @default.
• W2116728057 hasRelatedWork W1987407100 @default.
• W2116728057 hasRelatedWork W2011327495 @default.
• W2116728057 hasRelatedWork W2078054293 @default.
• W2116728057 hasRelatedWork W2116728057 @default.
• W2116728057 hasRelatedWork W2128939361 @default.
• W2116728057 hasRelatedWork W2134987486 @default.
• W2116728057 hasRelatedWork W2412499518 @default.

• next