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- W2116730131 abstract "Vesicular glutamate transporter (VGLUT) is responsible for the active transport of L-glutamate in synaptic vesicles and thus plays an essential role in the glutamatergic chemical transmission in the central nervous system. VGLUT comprises three isoforms, VGLUT1, 2, and 3, and is a potential marker for the glutamatergic phenotype. Recent studies indicated that VGLUT is also expressed in non-neuronal cells, and localized with various organelles such as synaptic-like microvesicles in the pineal gland, and hormone-containing secretory granules in endocrine cells. L-Glutamate is stored in these organelles, secreted upon various forms of stimulation, and then acts as a paracrine-like modulator. Thus, VGLUTs highlight a novel framework of glutamatergic signaling and reveal its diverse modes of action." @default.
- W2116730131 created "2016-06-24" @default.
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- W2116730131 date "2004-02-01" @default.
- W2116730131 modified "2023-10-17" @default.
- W2116730131 title "Glutamatergic Chemical Transmission: Look! Here, There, and Anywhere" @default.
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- W2116730131 doi "https://doi.org/10.1093/jb/mvh018" @default.
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