FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2116735936> ?p ?o ?g. }

• W2116735936 endingPage "451" @default.
• W2116735936 startingPage "441" @default.
• W2116735936 abstract "Many methods have been described to predict the subcellular location of proteins from sequence information. However, most of these methods either rely on global sequence properties or use a set of known protein targeting motifs to predict protein localization. Here, we develop and test a novel method that identifies potential targeting motifs using a discriminative approach based on hidden Markov models (discriminative HMMs). These models search for motifs that are present in a compartment but absent in other, nearby, compartments by utilizing an hierarchical structure that mimics the protein sorting mechanism. We show that both discriminative motif finding and the hierarchical structure improve localization prediction on a benchmark data set of yeast proteins. The motifs identified can be mapped to known targeting motifs and they are more conserved than the average protein sequence. Using our motif-based predictions, we can identify potential annotation errors in public databases for the location of some of the proteins. A software implementation and the data set described in this paper are available from http://murphylab.web.cmu.edu/software/2009_TCBB_motif/." @default.
• W2116735936 created "2016-06-24" @default.
• W2116735936 creator A5051163357 @default.
• W2116735936 creator A5061773929 @default.
• W2116735936 creator A5065673127 @default.
• W2116735936 date "2011-03-01" @default.
• W2116735936 modified "2023-09-25" @default.
• W2116735936 title "Discriminative Motif Finding for Predicting Protein Subcellular Localization" @default.
• W2116735936 cites W1480534106 @default.
• W2116735936 cites W1658092509 @default.
• W2116735936 cites W1786753252 @default.
• W2116735936 cites W1851748528 @default.
• W2116735936 cites W1966354073 @default.
• W2116735936 cites W1986492446 @default.
• W2116735936 cites W1987627338 @default.
• W2116735936 cites W1994704939 @default.
• W2116735936 cites W2003123121 @default.
• W2116735936 cites W2022366078 @default.
• W2116735936 cites W2028885314 @default.
• W2116735936 cites W2040630248 @default.
• W2116735936 cites W2041773495 @default.
• W2116735936 cites W2048102092 @default.
• W2116735936 cites W2054624670 @default.
• W2116735936 cites W2058682865 @default.
• W2116735936 cites W2061142076 @default.
• W2116735936 cites W2078381702 @default.
• W2116735936 cites W2098601596 @default.
• W2116735936 cites W2107080660 @default.
• W2116735936 cites W2108401170 @default.
• W2116735936 cites W2108420379 @default.
• W2116735936 cites W2108672476 @default.
• W2116735936 cites W2114066176 @default.
• W2116735936 cites W2117987251 @default.
• W2116735936 cites W2130147634 @default.
• W2116735936 cites W2139617657 @default.
• W2116735936 cites W2139848107 @default.
• W2116735936 cites W2141408320 @default.
• W2116735936 cites W2145091349 @default.
• W2116735936 cites W2145351317 @default.
• W2116735936 cites W2148252444 @default.
• W2116735936 cites W2148853951 @default.
• W2116735936 cites W2149822709 @default.
• W2116735936 cites W2151831732 @default.
• W2116735936 cites W2152458080 @default.
• W2116735936 cites W2153944330 @default.
• W2116735936 cites W2158173168 @default.
• W2116735936 cites W2169043568 @default.
• W2116735936 cites W2169777893 @default.
• W2116735936 cites W2169805130 @default.
• W2116735936 cites W2171091522 @default.
• W2116735936 doi "https://doi.org/10.1109/tcbb.2009.82" @default.
• W2116735936 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3050600" @default.
• W2116735936 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21233524" @default.
• W2116735936 hasPublicationYear "2011" @default.
• W2116735936 type Work @default.
• W2116735936 sameAs 2116735936 @default.
• W2116735936 citedByCount "33" @default.
• W2116735936 countsByYear W21167359362012 @default.
• W2116735936 countsByYear W21167359362013 @default.
• W2116735936 countsByYear W21167359362014 @default.
• W2116735936 countsByYear W21167359362015 @default.
• W2116735936 countsByYear W21167359362016 @default.
• W2116735936 countsByYear W21167359362017 @default.
• W2116735936 countsByYear W21167359362018 @default.
• W2116735936 countsByYear W21167359362019 @default.
• W2116735936 countsByYear W21167359362020 @default.
• W2116735936 countsByYear W21167359362021 @default.
• W2116735936 crossrefType "journal-article" @default.
• W2116735936 hasAuthorship W2116735936A5051163357 @default.
• W2116735936 hasAuthorship W2116735936A5061773929 @default.
• W2116735936 hasAuthorship W2116735936A5065673127 @default.
• W2116735936 hasBestOaLocation W21167359362 @default.
• W2116735936 hasConcept C10010492 @default.
• W2116735936 hasConcept C104317684 @default.
• W2116735936 hasConcept C117745874 @default.
• W2116735936 hasConcept C153180895 @default.
• W2116735936 hasConcept C154945302 @default.
• W2116735936 hasConcept C167625842 @default.
• W2116735936 hasConcept C23224414 @default.
• W2116735936 hasConcept C41008148 @default.
• W2116735936 hasConcept C54355233 @default.
• W2116735936 hasConcept C70721500 @default.
• W2116735936 hasConcept C86803240 @default.
• W2116735936 hasConcept C97931131 @default.
• W2116735936 hasConceptScore W2116735936C10010492 @default.
• W2116735936 hasConceptScore W2116735936C104317684 @default.
• W2116735936 hasConceptScore W2116735936C117745874 @default.
• W2116735936 hasConceptScore W2116735936C153180895 @default.
• W2116735936 hasConceptScore W2116735936C154945302 @default.
• W2116735936 hasConceptScore W2116735936C167625842 @default.
• W2116735936 hasConceptScore W2116735936C23224414 @default.
• W2116735936 hasConceptScore W2116735936C41008148 @default.
• W2116735936 hasConceptScore W2116735936C54355233 @default.
• W2116735936 hasConceptScore W2116735936C70721500 @default.
• W2116735936 hasConceptScore W2116735936C86803240 @default.
• W2116735936 hasConceptScore W2116735936C97931131 @default.
• W2116735936 hasIssue "2" @default.
• W2116735936 hasLocation W21167359361 @default.

• next