FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2116735996> ?p ?o ?g. }

• W2116735996 endingPage "35" @default.
• W2116735996 startingPage "26" @default.
• W2116735996 abstract "Nicotine, the major addictive component of tobacco, is an immunomodulator that impacts on many cells, including immune cells involved in inflammatory processes. Nicotine also induces oxidative damage to the vascular endothelium and accentuates lipid peroxidation, resulting in vascular cell dysfunction. Furthermore, vascular endothelial cells produce growth factors, such as cytokines and chemokines capable of stimulating and recruiting immune cells to atheromatous lesions. In addition, bacterial products including lipopolysaccharides (LPS), a major component of Gram negative bacterial cell walls, activate gene expression resulting in inflammatory cytokine production causing further damage to the vasculature. In the present study, the combined effects of nicotine and bacterial LPS on the expression of IL-6, IL-8, GRO-α and MCP-1 in cell lines of human coronary artery endothelial cells (HCAEC) and pulmonary monocytes (THP-1) were examined by quantitative real-time PCR and ELISA. Results showed that nicotine suppressed the LPS induced production of IL-6 and IL-8 in both cell lines. Since cytokines which alter homeostasis of both vascular endothelial and immune cells are critical for the atherogenic process, further studies are warranted to examine in detail the role of nicotine in terms of effects on inflammatory reactions, including those induced by bacterial infection." @default.
• W2116735996 created "2016-06-24" @default.
• W2116735996 creator A5009483614 @default.
• W2116735996 creator A5029987372 @default.
• W2116735996 creator A5060032068 @default.
• W2116735996 creator A5072207657 @default.
• W2116735996 creator A5081621071 @default.
• W2116735996 date "2006-01-01" @default.
• W2116735996 modified "2023-09-23" @default.
• W2116735996 title "Nicotine modulation of cytokine induction by LPS-stimulated human monocytes and coronary artery endothelial cells" @default.
• W2116735996 cites W1580033279 @default.
• W2116735996 cites W1603876339 @default.
• W2116735996 cites W1970563505 @default.
• W2116735996 cites W2014684433 @default.
• W2116735996 cites W2016990662 @default.
• W2116735996 cites W2023370536 @default.
• W2116735996 cites W2039674690 @default.
• W2116735996 cites W2041157072 @default.
• W2116735996 cites W2044201402 @default.
• W2116735996 cites W2044545339 @default.
• W2116735996 cites W2046641769 @default.
• W2116735996 cites W2052845314 @default.
• W2116735996 cites W2065957257 @default.
• W2116735996 cites W2078931357 @default.
• W2116735996 cites W2080884383 @default.
• W2116735996 cites W2082825335 @default.
• W2116735996 cites W2143318553 @default.
• W2116735996 cites W2148001826 @default.
• W2116735996 cites W2149030726 @default.
• W2116735996 cites W2153871823 @default.
• W2116735996 cites W2157653707 @default.
• W2116735996 cites W2158450811 @default.
• W2116735996 cites W2171821593 @default.
• W2116735996 cites W2177782459 @default.
• W2116735996 cites W23276643 @default.
• W2116735996 cites W2409458766 @default.
• W2116735996 doi "https://doi.org/10.1016/j.intimp.2005.07.005" @default.
• W2116735996 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16332510" @default.
• W2116735996 hasPublicationYear "2006" @default.
• W2116735996 type Work @default.
• W2116735996 sameAs 2116735996 @default.
• W2116735996 citedByCount "27" @default.
• W2116735996 countsByYear W21167359962012 @default.
• W2116735996 countsByYear W21167359962013 @default.
• W2116735996 countsByYear W21167359962014 @default.
• W2116735996 countsByYear W21167359962016 @default.
• W2116735996 countsByYear W21167359962017 @default.
• W2116735996 countsByYear W21167359962019 @default.
• W2116735996 countsByYear W21167359962020 @default.
• W2116735996 countsByYear W21167359962021 @default.
• W2116735996 countsByYear W21167359962022 @default.
• W2116735996 crossrefType "journal-article" @default.
• W2116735996 hasAuthorship W2116735996A5009483614 @default.
• W2116735996 hasAuthorship W2116735996A5029987372 @default.
• W2116735996 hasAuthorship W2116735996A5060032068 @default.
• W2116735996 hasAuthorship W2116735996A5072207657 @default.
• W2116735996 hasAuthorship W2116735996A5081621071 @default.
• W2116735996 hasConcept C123012128 @default.
• W2116735996 hasConcept C126322002 @default.
• W2116735996 hasConcept C13373296 @default.
• W2116735996 hasConcept C134018914 @default.
• W2116735996 hasConcept C202751555 @default.
• W2116735996 hasConcept C203014093 @default.
• W2116735996 hasConcept C2776914184 @default.
• W2116735996 hasConcept C2776992346 @default.
• W2116735996 hasConcept C2778690821 @default.
• W2116735996 hasConcept C2779547902 @default.
• W2116735996 hasConcept C55493867 @default.
• W2116735996 hasConcept C71924100 @default.
• W2116735996 hasConcept C86803240 @default.
• W2116735996 hasConcept C8891405 @default.
• W2116735996 hasConceptScore W2116735996C123012128 @default.
• W2116735996 hasConceptScore W2116735996C126322002 @default.
• W2116735996 hasConceptScore W2116735996C13373296 @default.
• W2116735996 hasConceptScore W2116735996C134018914 @default.
• W2116735996 hasConceptScore W2116735996C202751555 @default.
• W2116735996 hasConceptScore W2116735996C203014093 @default.
• W2116735996 hasConceptScore W2116735996C2776914184 @default.
• W2116735996 hasConceptScore W2116735996C2776992346 @default.
• W2116735996 hasConceptScore W2116735996C2778690821 @default.
• W2116735996 hasConceptScore W2116735996C2779547902 @default.
• W2116735996 hasConceptScore W2116735996C55493867 @default.
• W2116735996 hasConceptScore W2116735996C71924100 @default.
• W2116735996 hasConceptScore W2116735996C86803240 @default.
• W2116735996 hasConceptScore W2116735996C8891405 @default.
• W2116735996 hasIssue "1" @default.
• W2116735996 hasLocation W21167359961 @default.
• W2116735996 hasLocation W21167359962 @default.
• W2116735996 hasOpenAccess W2116735996 @default.
• W2116735996 hasPrimaryLocation W21167359961 @default.
• W2116735996 hasRelatedWork W1994888681 @default.
• W2116735996 hasRelatedWork W2005666125 @default.
• W2116735996 hasRelatedWork W2047209980 @default.
• W2116735996 hasRelatedWork W2050374169 @default.
• W2116735996 hasRelatedWork W2070463916 @default.
• W2116735996 hasRelatedWork W2126005292 @default.
• W2116735996 hasRelatedWork W4292317885 @default.
• W2116735996 hasRelatedWork W4321166026 @default.

• next