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- W2116737654 abstract "Polarization sensitive optical coherence tomography (PS-OCT) is a functional extension of conventional OCT and can assess depth-resolved tissue birefringence in addition to intensity. Most existing PS-OCT systems are relatively complex and their clinical translation remains difficult. We present a simple and robust all-fiber PS-OCT system based on swept source technology and polarization depth-encoding. Polarization multiplexing was achieved using a polarization maintaining fiber. Polarization sensitive signals were detected using fiber based polarization beam splitters and polarization controllers were used to remove the polarization ambiguity. A simplified post-processing algorithm was proposed for speckle noise reduction relaxing the demand for phase stability. We demonstrated systems design for both ophthalmic and catheter-based PS-OCT. For ophthalmic imaging, we used an optical clock frequency doubling method to extend the imaging range of a commercially available short cavity light source to improve polarization depth-encoding. For catheter based imaging, we demonstrated 200 kHz PS-OCT imaging using a MEMS-tunable vertical cavity surface emitting laser (VCSEL) and a high speed micromotor imaging catheter. The system was demonstrated in human retina, finger and lip imaging, as well as ex vivo swine esophagus and cardiovascular imaging. The all-fiber PS-OCT is easier to implement and maintain compared to previous PS-OCT systems and can be more easily translated to clinical applications due to its robust design." @default.
- W2116737654 created "2016-06-24" @default.
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- W2116737654 date "2014-08-01" @default.
- W2116737654 modified "2023-10-17" @default.
- W2116737654 title "Depth-encoded all-fiber swept source polarization sensitive OCT" @default.
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- W2116737654 doi "https://doi.org/10.1364/boe.5.002931" @default.
- W2116737654 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4230879" @default.
- W2116737654 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25401008" @default.
- W2116737654 hasPublicationYear "2014" @default.
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