Matches in SemOpenAlex for { <https://semopenalex.org/work/W2116739276> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2116739276 abstract "The major stimulus for erythropoietin secretion is the circulating hemoglobin level, but other poorly understood factors appear to influence the erythropoietin level as well. Therefore, the effect of cobalamin deficiency was studied in patients who were not anemic, even though many of them had macrocytosis or metabolic deficiency of the bone marrow cells. All 15 cobalamin-deficient patients without anemia had normal erythropoietin levels, including the 4 patients with macrocytosis and 3 in whom metabolic cobalamin deficiency of the marrow cells was documented with the deoxyuridine suppression test. Moreover, among 21 cobalamin-deficient patients with anemia, the 4 least anemic patients also had normal erythropoietin levels. The other 17 anemic patients had elevated erythropoietin levels. Erythropoietin levels correlated with the severity of the anemia (r = 0.423, p less than 0.05). However, wide individual variations were observed; 4 patients with hemoglobin levels of 37-43 g/l had erythropoietin levels ranging from 69 to 3300 units/l, for example. These observations support the hypothesis that the hemoglobin level is the major, but not the sole factor that determines erythropoietin levels. As long as it does not produce anemia, however, cobalamin deficiency does not raise erythropoietin levels even when it induces metabolic deficiency of the bone marrow and macrocytosis." @default.
- W2116739276 created "2016-06-24" @default.
- W2116739276 creator A5009677762 @default.
- W2116739276 creator A5063290032 @default.
- W2116739276 date "2009-04-24" @default.
- W2116739276 modified "2023-09-27" @default.
- W2116739276 title "Erythropoietin levels in cobalamin deficiency: Comparison of anemic and non-anemic, subtly deficient patients" @default.
- W2116739276 cites W10952140 @default.
- W2116739276 cites W186990880 @default.
- W2116739276 cites W1965041669 @default.
- W2116739276 cites W1970422462 @default.
- W2116739276 cites W1975162551 @default.
- W2116739276 cites W2021053694 @default.
- W2116739276 cites W2026083876 @default.
- W2116739276 cites W2031496147 @default.
- W2116739276 cites W2036114505 @default.
- W2116739276 cites W2047062282 @default.
- W2116739276 cites W2061804681 @default.
- W2116739276 cites W2069222290 @default.
- W2116739276 cites W2073036408 @default.
- W2116739276 cites W2080729254 @default.
- W2116739276 cites W2094744588 @default.
- W2116739276 cites W2168894365 @default.
- W2116739276 cites W2326469489 @default.
- W2116739276 cites W2328782968 @default.
- W2116739276 cites W4295371195 @default.
- W2116739276 doi "https://doi.org/10.1111/j.1600-0609.1992.tb00589.x" @default.
- W2116739276 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1559573" @default.
- W2116739276 hasPublicationYear "2009" @default.
- W2116739276 type Work @default.
- W2116739276 sameAs 2116739276 @default.
- W2116739276 citedByCount "6" @default.
- W2116739276 crossrefType "journal-article" @default.
- W2116739276 hasAuthorship W2116739276A5009677762 @default.
- W2116739276 hasAuthorship W2116739276A5063290032 @default.
- W2116739276 hasConcept C126322002 @default.
- W2116739276 hasConcept C134018914 @default.
- W2116739276 hasConcept C2778248108 @default.
- W2116739276 hasConcept C2778534260 @default.
- W2116739276 hasConcept C2778917026 @default.
- W2116739276 hasConcept C2779703530 @default.
- W2116739276 hasConcept C2779750884 @default.
- W2116739276 hasConcept C2780007613 @default.
- W2116739276 hasConcept C2780676250 @default.
- W2116739276 hasConcept C2780959883 @default.
- W2116739276 hasConcept C2781291160 @default.
- W2116739276 hasConcept C71924100 @default.
- W2116739276 hasConceptScore W2116739276C126322002 @default.
- W2116739276 hasConceptScore W2116739276C134018914 @default.
- W2116739276 hasConceptScore W2116739276C2778248108 @default.
- W2116739276 hasConceptScore W2116739276C2778534260 @default.
- W2116739276 hasConceptScore W2116739276C2778917026 @default.
- W2116739276 hasConceptScore W2116739276C2779703530 @default.
- W2116739276 hasConceptScore W2116739276C2779750884 @default.
- W2116739276 hasConceptScore W2116739276C2780007613 @default.
- W2116739276 hasConceptScore W2116739276C2780676250 @default.
- W2116739276 hasConceptScore W2116739276C2780959883 @default.
- W2116739276 hasConceptScore W2116739276C2781291160 @default.
- W2116739276 hasConceptScore W2116739276C71924100 @default.
- W2116739276 hasLocation W21167392761 @default.
- W2116739276 hasLocation W21167392762 @default.
- W2116739276 hasOpenAccess W2116739276 @default.
- W2116739276 hasPrimaryLocation W21167392761 @default.
- W2116739276 hasRelatedWork W1971076858 @default.
- W2116739276 hasRelatedWork W2005410488 @default.
- W2116739276 hasRelatedWork W2064617886 @default.
- W2116739276 hasRelatedWork W2068881202 @default.
- W2116739276 hasRelatedWork W2116739276 @default.
- W2116739276 hasRelatedWork W2118925163 @default.
- W2116739276 hasRelatedWork W2158399804 @default.
- W2116739276 hasRelatedWork W2401390217 @default.
- W2116739276 hasRelatedWork W2414353598 @default.
- W2116739276 hasRelatedWork W4225256964 @default.
- W2116739276 isParatext "false" @default.
- W2116739276 isRetracted "false" @default.
- W2116739276 magId "2116739276" @default.
- W2116739276 workType "article" @default.