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• W2116741443 abstract "A history of an escalating chronic intractable pain in a patient with cryoglobulinemia, vasculitis, and severe cutaneous ulcerations is presented. A strategy of progressive, multi-agent, N-methyl-D-aspartate-receptor (NMDA-R) blockade that resulted in adequate pain control and a three-fold reduction in opioid consumption is described. Diagnostic process of neuropathic pain and the role of NMDA-R in the development of hyperalgesia are briefly reviewed. Thereafter, existing clinical literature describing the use of Ketamine, a major NMDA-R antagonist for management of malignant pain, is reviewed. Lastly, evidence-based original protocol for intravenous adjuvant Ketamine analgesia for severe cancer pain is presented. Key Words: Cancer, Ketamine, pain" @default.
• W2116741443 created "2016-06-24" @default.
• W2116741443 creator A5039590340 @default.
• W2116741443 date "2007-05-14" @default.
• W2116741443 modified "2023-09-29" @default.
• W2116741443 title "Ketamine: An Introduction for the Pain and Palliative Medicine Physician" @default.
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• W2116741443 doi "https://doi.org/10.36076/ppj.2007/10/493" @default.
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