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- W2116742949 abstract "Objectives To determine whether the risk of external auditory canal stenosis from external-beam radiation therapy is dose dependent. Study Design Retrospective chart review. Methods The presence of external auditory canal disease was recorded for patients who received low-dose (e.g., lymphoma [20–40 Gy]), medium-dose (e.g., chemodectoma [40–55 Gy]), or high-dose (e.g., parotid and nasopharyngeal neoplasms [55–75 Gy]) external-beam radiation therapy from 6 months to over 8 years following treatment. The incidence of external auditory canal disease was compared between groups. Results None of 13 low-dose, none of 19 medium-dose, and 8 of 91 (8.7%) high-dose external-beam radiation therapy subjects developed ipsilateral external auditory canal stenosis. No external auditory canal stenosis developed in patients treated with high-dose external-beam radiation therapy in the absence of parotid surgery. External auditory canal stenosis developed only in patients treated with parotidectomy and high-dose external-beam radiation therapy (P = .0059), and all of these cases of external auditory canal stenosis developed within 3 years of radiation therapy. Conclusions High dose external-beam radiation therapy alone does not significantly predispose patients to external auditory canal stenosis. However, combined high-dose external-beam radiation therapy and surgery around the external auditory canal do significantly increase the risk of external auditory canal stenosis." @default.
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- W2116742949 date "2002-11-01" @default.
- W2116742949 modified "2023-09-28" @default.
- W2116742949 title "External Auditory Canal Stenosis After Radiation Therapy" @default.
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- W2116742949 doi "https://doi.org/10.1097/00005537-200211000-00012" @default.
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