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- W2116745204 endingPage "1848" @default.
- W2116745204 startingPage "1837" @default.
- W2116745204 abstract "Intermediate filaments (IFs) are a key component of the cytoskeleton in virtually all vertebrate cells, including those of the lens of the eye. IFs help integrate individual cells into their respective tissues. This Review focuses on the lens-specific IF proteins beaded filament structural proteins 1 and 2 (BFSP1 and BFSP2) and their role in lens physiology and disease. Evidence generated in studies in both mice and humans suggests a critical role for these proteins and their filamentous polymers in establishing the optical properties of the eye lens and in maintaining its transparency. For instance, mutations in both BFSP1 and BFSP2 cause cataract in humans. We also explore the potential role of BFSP1 and BFSP2 in aging processes in the lens." @default.
- W2116745204 created "2016-06-24" @default.
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- W2116745204 creator A5091048090 @default.
- W2116745204 date "2009-07-01" @default.
- W2116745204 modified "2023-09-30" @default.
- W2116745204 title "Functions of the intermediate filament cytoskeleton in the eye lens" @default.
- W2116745204 cites W1495025346 @default.
- W2116745204 cites W158612420 @default.
- W2116745204 cites W1604252033 @default.
- W2116745204 cites W1755868117 @default.
- W2116745204 cites W1822372593 @default.
- W2116745204 cites W1910989283 @default.
- W2116745204 cites W1942474975 @default.
- W2116745204 cites W1967830527 @default.
- W2116745204 cites W1969678140 @default.
- W2116745204 cites W1973444843 @default.
- W2116745204 cites W1975629872 @default.
- W2116745204 cites W1976327882 @default.
- W2116745204 cites W1978444841 @default.
- W2116745204 cites W1979978460 @default.
- W2116745204 cites W1981477992 @default.
- W2116745204 cites W1983146026 @default.
- W2116745204 cites W1984564086 @default.
- W2116745204 cites W1988028255 @default.
- W2116745204 cites W1988866780 @default.
- W2116745204 cites W1991666936 @default.
- W2116745204 cites W1992799875 @default.
- W2116745204 cites W1995134804 @default.
- W2116745204 cites W1998729868 @default.
- W2116745204 cites W1999333109 @default.
- W2116745204 cites W2003008933 @default.
- W2116745204 cites W2007532218 @default.
- W2116745204 cites W2007682992 @default.
- W2116745204 cites W2008726342 @default.
- W2116745204 cites W2008975203 @default.
- W2116745204 cites W2009717367 @default.
- W2116745204 cites W2011409902 @default.
- W2116745204 cites W2011704620 @default.
- W2116745204 cites W2013344195 @default.
- W2116745204 cites W2013750644 @default.
- W2116745204 cites W2013898010 @default.
- W2116745204 cites W2016230197 @default.
- W2116745204 cites W2018438428 @default.
- W2116745204 cites W2023318498 @default.
- W2116745204 cites W2023662333 @default.
- W2116745204 cites W2023703673 @default.
- W2116745204 cites W2023829520 @default.
- W2116745204 cites W2034369280 @default.
- W2116745204 cites W2036492151 @default.
- W2116745204 cites W2036682047 @default.
- W2116745204 cites W2038065381 @default.
- W2116745204 cites W2043193854 @default.
- W2116745204 cites W2044222075 @default.
- W2116745204 cites W2046611480 @default.
- W2116745204 cites W2047217941 @default.
- W2116745204 cites W2050201900 @default.
- W2116745204 cites W2052111966 @default.
- W2116745204 cites W2053202443 @default.
- W2116745204 cites W2053473203 @default.
- W2116745204 cites W2057762926 @default.
- W2116745204 cites W2058554145 @default.
- W2116745204 cites W2059781219 @default.
- W2116745204 cites W2060086170 @default.
- W2116745204 cites W2060176013 @default.
- W2116745204 cites W2064828019 @default.
- W2116745204 cites W2067852794 @default.
- W2116745204 cites W2068336388 @default.
- W2116745204 cites W2069073212 @default.
- W2116745204 cites W2070027200 @default.
- W2116745204 cites W2074947501 @default.
- W2116745204 cites W2075373463 @default.
- W2116745204 cites W2080860664 @default.
- W2116745204 cites W2081053846 @default.
- W2116745204 cites W2082937294 @default.
- W2116745204 cites W2083673761 @default.
- W2116745204 cites W2084190552 @default.
- W2116745204 cites W2084227370 @default.
- W2116745204 cites W2086963517 @default.
- W2116745204 cites W2087555682 @default.
- W2116745204 cites W2088999402 @default.
- W2116745204 cites W2089229694 @default.
- W2116745204 cites W2091509097 @default.
- W2116745204 cites W2096384092 @default.
- W2116745204 cites W2097884838 @default.
- W2116745204 cites W2100628439 @default.
- W2116745204 cites W2105404391 @default.
- W2116745204 cites W2112660188 @default.
- W2116745204 cites W2114177119 @default.
- W2116745204 cites W2115122955 @default.
- W2116745204 cites W2115644880 @default.
- W2116745204 cites W2116426914 @default.
- W2116745204 cites W2118288719 @default.
- W2116745204 cites W2120412594 @default.