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- W2116750889 abstract "During meiosis, the paired homologous chromosomes are tightly held together by the synaptonemal complex (SC). This complex consists of two parallel axial/lateral elements (AEs/LEs) and one central element. Here, we observed that PAIR3 localized to the chromosome core during prophase I and associated with both unsynapsed AEs and synapsed LEs. Analyses of the severe pair3 mutant demonstrated that PAIR3 was essential for bouquet formation, homologous pairing and normal recombination, and SC assembly. In addition, we showed that although PAIR3 was not required for the initial recruitment of PAIR2, it was required for the proper association of PAIR2 with chromosomes. Dual immunostaining revealed that PAIR3 highly colocalized with REC8. Moreover, studies using a rec8 mutant indicated that PAIR3 localized to chromosomes in a REC8-dependent manner." @default.
- W2116750889 created "2016-06-24" @default.
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- W2116750889 date "2011-01-01" @default.
- W2116750889 modified "2023-09-28" @default.
- W2116750889 title "PAIR3, an axis-associated protein, is essential for the recruitment of recombination elements onto meiotic chromosomes in rice" @default.
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- W2116750889 doi "https://doi.org/10.1091/mbc.e10-08-0667" @default.
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