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- W2116760536 endingPage "246" @default.
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- W2116760536 abstract "Subclinical hypothyroidism (SCH) is a common disorder that is characterized by elevated thyroid-stimulating hormone levels in conjunction with free thyroxine concentrations within the normal reference range. Thyroid hormones are known to affect the heart and vasculature and, as a result, the impact of SCH on the cardiovascular (CV) system has recently become an important topic of research. Strong evidence points to a link between SCH and CV risk factors such as alterations in blood pressure, lipid levels, and atherosclerosis. Additionally, accumulating evidence indicates that SCH is associated with metabolic syndrome and heart failure. The present review proposes that SCH may be a potentially modifiable risk factor of CV disease and mortality. However, large-scale clinical trials with appropriate power investigating the risks and benefits of SCH treatment are required to determine whether these benefits can be achieved with levothyroxine therapy." @default.
- W2116760536 created "2016-06-24" @default.
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- W2116760536 date "2015-01-01" @default.
- W2116760536 modified "2023-09-28" @default.
- W2116760536 title "Subclinical Hypothyroidism and Cardiovascular Disease" @default.
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- W2116760536 doi "https://doi.org/10.3803/enm.2015.30.3.246" @default.
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