FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2116774693> ?p ?o ?g. }

• W2116774693 endingPage "1222" @default.
• W2116774693 startingPage "1215" @default.
• W2116774693 abstract "Crimean–Congo haemorrhagic fever (CCHF) is a potentially fatal tick-borne infection. The virus is widely distributed around the world and reports of sporadic cases and outbreaks have recently increased significantly. Some authors have proposed that ribavirin improves survival in CCHF and this view appears to be widely accepted. We evaluated the efficacy of ribavirin in reducing mortality by conducting a systematic review and meta-analysis. We included randomized controlled trials and observational studies that compared the outcomes of CCHF patients who were treated with ribavirin with those of patients that were not treated. The main endpoint we assessed was survival. We also evaluated secondary endpoints, i.e. adverse events, length of stay in the hospital, time taken for laboratory values to return to normal and requirement for blood products. A pooled estimate of the relative risks for survival from each study was obtained by using random effects models. One randomized controlled trial and seven observational studies met our inclusion criteria. Most observational studies suffered from different types of bias due to inappropriate selection of controls. Compilation of data from all included studies showed that ribavirin did not improve survival in CCHF (relative risk 1.06, 95% confidence interval 0.97–1.16). Analysis of secondary endpoints did not suggest a clinically significant beneficial effect either. Our systematic review and meta-analysis revealed that the available data in the literature are inadequate to support a claim of efficacy of ribavirin in CCHF. We believe a real uncertainty exists over the benefit of ribavirin in the treatment of CCHF, which necessitates the urgent conduct of a randomized placebo-controlled trial." @default.
• W2116774693 created "2016-06-24" @default.
• W2116774693 creator A5025009795 @default.
• W2116774693 creator A5045255444 @default.
• W2116774693 creator A5067202025 @default.
• W2116774693 creator A5084753842 @default.
• W2116774693 date "2011-04-11" @default.
• W2116774693 modified "2023-10-17" @default.
• W2116774693 title "Ribavirin for patients with Crimean–Congo haemorrhagic fever: a systematic review and meta-analysis" @default.
• W2116774693 cites W1593633973 @default.
• W2116774693 cites W192855520 @default.
• W2116774693 cites W1965387930 @default.
• W2116774693 cites W1970835801 @default.
• W2116774693 cites W1975084994 @default.
• W2116774693 cites W1975106131 @default.
• W2116774693 cites W1977563441 @default.
• W2116774693 cites W1979190970 @default.
• W2116774693 cites W1979423827 @default.
• W2116774693 cites W1980058768 @default.
• W2116774693 cites W1981501248 @default.
• W2116774693 cites W1982375973 @default.
• W2116774693 cites W1982489161 @default.
• W2116774693 cites W1995345282 @default.
• W2116774693 cites W1996924502 @default.
• W2116774693 cites W2005501262 @default.
• W2116774693 cites W2020938276 @default.
• W2116774693 cites W2028717340 @default.
• W2116774693 cites W2030206448 @default.
• W2116774693 cites W2032056733 @default.
• W2116774693 cites W2032182314 @default.
• W2116774693 cites W2033890227 @default.
• W2116774693 cites W2050828759 @default.
• W2116774693 cites W2052984045 @default.
• W2116774693 cites W2067001596 @default.
• W2116774693 cites W2074034555 @default.
• W2116774693 cites W2075064465 @default.
• W2116774693 cites W2084917404 @default.
• W2116774693 cites W2087522384 @default.
• W2116774693 cites W2090226269 @default.
• W2116774693 cites W2091031254 @default.
• W2116774693 cites W2091370980 @default.
• W2116774693 cites W2093188984 @default.
• W2116774693 cites W2099179453 @default.
• W2116774693 cites W2112365180 @default.
• W2116774693 cites W2127875776 @default.
• W2116774693 cites W2129184914 @default.
• W2116774693 cites W2134453018 @default.
• W2116774693 cites W2134759021 @default.
• W2116774693 cites W2136048242 @default.
• W2116774693 cites W2136166622 @default.
• W2116774693 cites W2138218432 @default.
• W2116774693 cites W2143633444 @default.
• W2116774693 cites W2145639634 @default.
• W2116774693 cites W2148855007 @default.
• W2116774693 cites W2149787764 @default.
• W2116774693 cites W2151161022 @default.
• W2116774693 cites W2154292852 @default.
• W2116774693 cites W2170504655 @default.
• W2116774693 cites W4233735885 @default.
• W2116774693 cites W4244267183 @default.
• W2116774693 doi "https://doi.org/10.1093/jac/dkr136" @default.
• W2116774693 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21482564" @default.
• W2116774693 hasPublicationYear "2011" @default.
• W2116774693 type Work @default.
• W2116774693 sameAs 2116774693 @default.
• W2116774693 citedByCount "93" @default.
• W2116774693 countsByYear W21167746932012 @default.
• W2116774693 countsByYear W21167746932013 @default.
• W2116774693 countsByYear W21167746932014 @default.
• W2116774693 countsByYear W21167746932015 @default.
• W2116774693 countsByYear W21167746932016 @default.
• W2116774693 countsByYear W21167746932017 @default.
• W2116774693 countsByYear W21167746932018 @default.
• W2116774693 countsByYear W21167746932019 @default.
• W2116774693 countsByYear W21167746932020 @default.
• W2116774693 countsByYear W21167746932021 @default.
• W2116774693 countsByYear W21167746932022 @default.
• W2116774693 countsByYear W21167746932023 @default.
• W2116774693 crossrefType "journal-article" @default.
• W2116774693 hasAuthorship W2116774693A5025009795 @default.
• W2116774693 hasAuthorship W2116774693A5045255444 @default.
• W2116774693 hasAuthorship W2116774693A5067202025 @default.
• W2116774693 hasAuthorship W2116774693A5084753842 @default.
• W2116774693 hasBestOaLocation W21167746931 @default.
• W2116774693 hasConcept C126322002 @default.
• W2116774693 hasConcept C159047783 @default.
• W2116774693 hasConcept C168563851 @default.
• W2116774693 hasConcept C177713679 @default.
• W2116774693 hasConcept C197934379 @default.
• W2116774693 hasConcept C203092338 @default.
• W2116774693 hasConcept C23131810 @default.
• W2116774693 hasConcept C2522874641 @default.
• W2116774693 hasConcept C2776408679 @default.
• W2116774693 hasConcept C2780040827 @default.
• W2116774693 hasConcept C44249647 @default.
• W2116774693 hasConcept C71924100 @default.
• W2116774693 hasConcept C82789193 @default.
• W2116774693 hasConcept C95190672 @default.

• next