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• W2116780926 abstract "Contusion injuries are a very common form of both athletic and non-athletic injury, that effect muscle function. Treatments to augment the normal repair and regeneration processes are important for a wide variety of patients. Therapeutic ultrasound has been claimed to promote tissue repair, especially by enhancing cell proliferation and protein synthesis. The present study aimed to investigate the effect of therapeutic pulsed ultrasound (TPU) on parameters of oxidative stress, namely thiobarbituric acid-reactive substances (TBARS), protein carbonyl content and the activities of antioxidant enzymes, catalase and superoxide dismutase (SOD), in skeletal muscle after injury. Wistar rats were submitted to an animal model of muscle (gastrocnemius) laceration. TPU was used once a day. One, three or five days after muscle laceration, the animals were killed by decapitation and oxidative stress parameters were evaluated. Serum CK levels were increased in muscle-injured animals, indicating that the laceration animal model was successful. TBARS were not altered after muscle injury, when compared to the sham group. Protein carbonyl content was increased after muscle laceration. Catalase and SOD activities were increased 1 day after muscle injury and not altered at days 3 and 5. TPU decreased TBARS levels after muscle laceration when compared to injured muscle animals without treatment. Protein carbonyl content evaluation presented similar results. It is tempting to speculate that TPU seems to protect the tissue from oxidative injury. TPU diminished catalase and SOD activities, especially on the first day following muscle laceration." @default.
• W2116780926 created "2016-06-24" @default.
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• W2116780926 date "2007-05-01" @default.
• W2116780926 modified "2023-10-03" @default.
• W2116780926 title "Effect of therapeutic pulsed ultrasound on parameters of oxidative stress in skeletal muscle after injury" @default.
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• W2116780926 doi "https://doi.org/10.1016/j.cellbi.2006.11.015" @default.
• W2116780926 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17196843" @default.
• W2116780926 hasPublicationYear "2007" @default.
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