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- W2116783959 abstract "The purpose of this study was to identify the temporal sequence of cellular changes in the glenoid fossa and to quantify the amount of bone formation in response to mandibular advancement. One hundred 35-day-old female Sprague-Dawley rats were randomly divided into 5 experimental groups (15 rats each) and 5 control groups (5 rats each). In the experimental groups, functional appliances were used to create continuous forward mandibular advancement. The rats were killed after 3, 7, 14, 21, and 30 days. Sections were cut through the glenoid fossa in the parasagittal plane and stained with periodic acid and Schiff's reagent for evaluation of bone formation and with hematoxylin and eosin for observation of cellular response. The results showed that, in the control rats, bone formation was initially higher in the posterior and middle regions than in the anterior region then decreased over time in all regions. In the experimental group, bone formation significantly increased from day 7 to day 30 compared with control rats. Day 21 marked the highest levels of bone formation in the middle (+184%) and posterior regions (+300%). Mandibular protrusion resulted in the osteoprogenitor cells being oriented in the direction of the pull of the posterior fibers of the disc and also resulted in a considerable increase in bone formation in the glenoid fossa. (Am J Orthod Dentofacial Orthop 2001;119:390-400)" @default.
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- W2116783959 date "1970-10-01" @default.
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- W2116783959 title "The effect of a Class II intermaxillary force on the dentofacial complex in the adult Macaca mulatta monkey" @default.
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- W2116783959 doi "https://doi.org/10.1016/0002-9416(70)90104-1" @default.
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