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• W2116788622 abstract "2-Arylamino-4-trifluoromethyl-5-aminomethylthiazoles represent a novel series of high-affinity corticotropin releasing factor-1 receptor (CRF1R) antagonists that are prepared in three steps in good overall yields. Herein, we report binding SAR as well as anxiolytic activity of an exemplary compound (7a, Ki=8.6 nM) in a mouse canopy model." @default.
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• W2116788622 date "2003-11-01" @default.
• W2116788622 modified "2023-09-26" @default.
• W2116788622 title "2-Arylaminothiazoles as high-affinity corticotropin-Releasing factor 1 receptor (CRF1R) antagonists: synthesis, binding studies and behavioral efficacy" @default.
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• W2116788622 doi "https://doi.org/10.1016/j.bmcl.2003.08.055" @default.
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