FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2116794174> ?p ?o ?g. }

• W2116794174 endingPage "1632" @default.
• W2116794174 startingPage "1624" @default.
• W2116794174 abstract "Determining linkage phase from population samples with statistical methods is accurate only within regions of high linkage disequilibrium (LD). Yet, affected individuals in a genetic mapping study, including those involving cases and controls, may share sequences identical-by-descent stretching on the order of 10s to 100s of kilobases, quite possibly over regions of low LD in the population. At the same time, inferring phase from nuclear families may be hampered by missing family members, missing genotypes, and the noninformativity of certain genotype patterns. In this study, we reformulate our previous haplotype reconstruction algorithm, and its associated computer program, to phase parents with information derived from population samples as well as from their offspring. In applications of our algorithm to 100-kb stretches, simulated in accordance to a Wright-Fisher model with typical levels of LD in humans, we find that phase reconstruction for 160 trios with 10% missing data is highly accurate (>90%) over the entire length. Furthermore, our algorithm can estimate allelic status for missing data at high accuracy (>95%). Finally, the input capacity of the program is vast, easily handling thousands of segregating sites in > or = 1000 chromosomes." @default.
• W2116794174 created "2016-06-24" @default.
• W2116794174 creator A5006598488 @default.
• W2116794174 creator A5031417789 @default.
• W2116794174 creator A5073552534 @default.
• W2116794174 date "2004-07-15" @default.
• W2116794174 modified "2023-09-23" @default.
• W2116794174 title "Haplotype and Missing Data Inference in Nuclear Families" @default.
• W2116794174 cites W1519466388 @default.
• W2116794174 cites W1543868019 @default.
• W2116794174 cites W1891283710 @default.
• W2116794174 cites W1958158305 @default.
• W2116794174 cites W1962960380 @default.
• W2116794174 cites W1964830464 @default.
• W2116794174 cites W1964901903 @default.
• W2116794174 cites W1967318355 @default.
• W2116794174 cites W1971771243 @default.
• W2116794174 cites W1999582374 @default.
• W2116794174 cites W2010498635 @default.
• W2116794174 cites W2021535444 @default.
• W2116794174 cites W2021805308 @default.
• W2116794174 cites W2021975834 @default.
• W2116794174 cites W2029361834 @default.
• W2116794174 cites W2042103448 @default.
• W2116794174 cites W2050730569 @default.
• W2116794174 cites W2050741655 @default.
• W2116794174 cites W2054017030 @default.
• W2116794174 cites W2074754379 @default.
• W2116794174 cites W2079501979 @default.
• W2116794174 cites W2082863489 @default.
• W2116794174 cites W2083878136 @default.
• W2116794174 cites W2106298744 @default.
• W2116794174 cites W2107871825 @default.
• W2116794174 cites W2109347434 @default.
• W2116794174 cites W2110755408 @default.
• W2116794174 cites W2116652744 @default.
• W2116794174 cites W2129559300 @default.
• W2116794174 cites W2133857505 @default.
• W2116794174 cites W2134599124 @default.
• W2116794174 cites W2145185240 @default.
• W2116794174 cites W2152626773 @default.
• W2116794174 cites W2153127576 @default.
• W2116794174 cites W2154097633 @default.
• W2116794174 cites W2159267146 @default.
• W2116794174 cites W2160782760 @default.
• W2116794174 cites W2486715829 @default.
• W2116794174 cites W2497588219 @default.
• W2116794174 cites W4243389179 @default.
• W2116794174 cites W4248237286 @default.
• W2116794174 doi "https://doi.org/10.1101/gr.2204604" @default.
• W2116794174 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/509272" @default.
• W2116794174 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15256514" @default.
• W2116794174 hasPublicationYear "2004" @default.
• W2116794174 type Work @default.
• W2116794174 sameAs 2116794174 @default.
• W2116794174 citedByCount "48" @default.
• W2116794174 countsByYear W21167941742012 @default.
• W2116794174 countsByYear W21167941742013 @default.
• W2116794174 countsByYear W21167941742014 @default.
• W2116794174 countsByYear W21167941742015 @default.
• W2116794174 countsByYear W21167941742016 @default.
• W2116794174 countsByYear W21167941742019 @default.
• W2116794174 countsByYear W21167941742020 @default.
• W2116794174 crossrefType "journal-article" @default.
• W2116794174 hasAuthorship W2116794174A5006598488 @default.
• W2116794174 hasAuthorship W2116794174A5031417789 @default.
• W2116794174 hasAuthorship W2116794174A5073552534 @default.
• W2116794174 hasBestOaLocation W21167941741 @default.
• W2116794174 hasConcept C104317684 @default.
• W2116794174 hasConcept C105795698 @default.
• W2116794174 hasConcept C135763542 @default.
• W2116794174 hasConcept C144024400 @default.
• W2116794174 hasConcept C149923435 @default.
• W2116794174 hasConcept C154945302 @default.
• W2116794174 hasConcept C178221405 @default.
• W2116794174 hasConcept C197754878 @default.
• W2116794174 hasConcept C2776214188 @default.
• W2116794174 hasConcept C2908647359 @default.
• W2116794174 hasConcept C31266012 @default.
• W2116794174 hasConcept C33923547 @default.
• W2116794174 hasConcept C35605836 @default.
• W2116794174 hasConcept C41008148 @default.
• W2116794174 hasConcept C54355233 @default.
• W2116794174 hasConcept C86803240 @default.
• W2116794174 hasConcept C9357733 @default.
• W2116794174 hasConceptScore W2116794174C104317684 @default.
• W2116794174 hasConceptScore W2116794174C105795698 @default.
• W2116794174 hasConceptScore W2116794174C135763542 @default.
• W2116794174 hasConceptScore W2116794174C144024400 @default.
• W2116794174 hasConceptScore W2116794174C149923435 @default.
• W2116794174 hasConceptScore W2116794174C154945302 @default.
• W2116794174 hasConceptScore W2116794174C178221405 @default.
• W2116794174 hasConceptScore W2116794174C197754878 @default.
• W2116794174 hasConceptScore W2116794174C2776214188 @default.
• W2116794174 hasConceptScore W2116794174C2908647359 @default.
• W2116794174 hasConceptScore W2116794174C31266012 @default.
• W2116794174 hasConceptScore W2116794174C33923547 @default.
• W2116794174 hasConceptScore W2116794174C35605836 @default.

• next