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• W2116794461 endingPage "141" @default.
• W2116794461 startingPage "121" @default.
• W2116794461 abstract "SUMMARY The cell wall of Candida albicans not only is the structure in which many biological functions essential for the fungal cells reside but also is a significant source of candidal antigens. The major cell wall components that elicit a response from the host immune system are proteins and glycoproteins, the latter being predominantly mannoproteins. Both the carbohydrate and protein moieties are able to trigger immune responses. Although cell-mediated immunity is often considered to be the most important line of defense against candidiasis, cell wall protein and glycoprotein components also elicit a potent humoral response from the host that may include some protective antibodies. Proteins and glycoproteins exposed at the most external layers of the wall structure are involved in several types of interactions of fungal cells with the exocellular environment. Thus, coating of fungal cells with host antibodies has the potential to influence profoundly the host-parasite interaction by affecting antibody-mediated functions such as opsonin-enhanced phagocytosis and blocking the binding activity of fungal adhesins for host ligands. In this review, the various members of the protein and glycoprotein fraction of the C. albicans cell wall that elicit an antibody response in vivo are examined. Although a number of proteins have been shown to stimulate an antibody response, for some of these species the response is not universal. On the other hand, some of the studies demonstrate that certain cell wall antigens and anti-cell wall antibodies may be the basis for developing specific and sensitive serologic tests for the diagnosis of candidasis, particularly the disseminated form. In addition, recent studies have focused on the potential for antibodies to cell wall protein determinants to protect the host against infection. Hence, a better understanding of the humoral response to cell wall antigens of C. albicans may provide the basis for the development of (i) effective procedures for the serodiagnosis of disseminated candidiasis and (ii) novel prophylactic (vaccination) and therapeutic strategies for the management of this type of infection." @default.
• W2116794461 created "2016-06-24" @default.
• W2116794461 creator A5022852723 @default.
• W2116794461 creator A5034134782 @default.
• W2116794461 creator A5059131009 @default.
• W2116794461 creator A5071209698 @default.
• W2116794461 date "1998-01-01" @default.
• W2116794461 modified "2023-10-18" @default.
• W2116794461 title "Serologic Response to Cell Wall Mannoproteins and Proteins of<i>Candida albicans</i>" @default.
• W2116794461 cites W100369038 @default.
• W2116794461 cites W143123087 @default.
• W2116794461 cites W1480790019 @default.
• W2116794461 cites W1505285433 @default.
• W2116794461 cites W1506283868 @default.
• W2116794461 cites W1525653538 @default.
• W2116794461 cites W1543731498 @default.
• W2116794461 cites W1549061932 @default.
• W2116794461 cites W1550656373 @default.
• W2116794461 cites W156022988 @default.
• W2116794461 cites W1562282158 @default.
• W2116794461 cites W1565479825 @default.
• W2116794461 cites W1568303301 @default.
• W2116794461 cites W1577445019 @default.
• W2116794461 cites W1583247515 @default.
• W2116794461 cites W1587920314 @default.
• W2116794461 cites W1623436378 @default.
• W2116794461 cites W1623447164 @default.
• W2116794461 cites W1625988767 @default.
• W2116794461 cites W1646707181 @default.
• W2116794461 cites W1667261212 @default.
• W2116794461 cites W1673608686 @default.
• W2116794461 cites W1677302622 @default.
• W2116794461 cites W1709657781 @default.
• W2116794461 cites W1739373483 @default.
• W2116794461 cites W1760120130 @default.
• W2116794461 cites W1764490041 @default.
• W2116794461 cites W1778564703 @default.
• W2116794461 cites W1789782051 @default.
• W2116794461 cites W1795136523 @default.
• W2116794461 cites W1805917040 @default.
• W2116794461 cites W1806627819 @default.
• W2116794461 cites W1816109389 @default.
• W2116794461 cites W1820239107 @default.
• W2116794461 cites W1832026901 @default.
• W2116794461 cites W1835941132 @default.
• W2116794461 cites W1836452804 @default.
• W2116794461 cites W1847725864 @default.
• W2116794461 cites W1852827861 @default.
• W2116794461 cites W1858131419 @default.
• W2116794461 cites W1872260506 @default.
• W2116794461 cites W1878458665 @default.
• W2116794461 cites W1880167351 @default.
• W2116794461 cites W1885188225 @default.
• W2116794461 cites W1886048289 @default.
• W2116794461 cites W1890684887 @default.
• W2116794461 cites W1896603219 @default.
• W2116794461 cites W1899434493 @default.
• W2116794461 cites W1902891146 @default.
• W2116794461 cites W1902912800 @default.
• W2116794461 cites W1904330388 @default.
• W2116794461 cites W1907950934 @default.
• W2116794461 cites W1907959623 @default.
• W2116794461 cites W1916539222 @default.
• W2116794461 cites W1916580572 @default.
• W2116794461 cites W1916807249 @default.
• W2116794461 cites W1916931565 @default.
• W2116794461 cites W1917288649 @default.
• W2116794461 cites W1919706581 @default.
• W2116794461 cites W1926758670 @default.
• W2116794461 cites W1928258841 @default.
• W2116794461 cites W1928795921 @default.
• W2116794461 cites W1930370363 @default.
• W2116794461 cites W1934710754 @default.
• W2116794461 cites W1936199135 @default.
• W2116794461 cites W1937936144 @default.
• W2116794461 cites W1937941011 @default.
• W2116794461 cites W1939297816 @default.
• W2116794461 cites W1941362262 @default.
• W2116794461 cites W1945490231 @default.
• W2116794461 cites W1948343381 @default.
• W2116794461 cites W1948650149 @default.
• W2116794461 cites W1951872079 @default.
• W2116794461 cites W1952545347 @default.
• W2116794461 cites W1962989573 @default.
• W2116794461 cites W1966955071 @default.
• W2116794461 cites W1967444231 @default.
• W2116794461 cites W1968051636 @default.
• W2116794461 cites W1968155668 @default.
• W2116794461 cites W1969952426 @default.
• W2116794461 cites W1970405892 @default.
• W2116794461 cites W1972109854 @default.
• W2116794461 cites W1972219874 @default.
• W2116794461 cites W1973413265 @default.
• W2116794461 cites W1973518711 @default.
• W2116794461 cites W1974872240 @default.
• W2116794461 cites W1976572404 @default.
• W2116794461 cites W1977024043 @default.
• W2116794461 cites W1978457777 @default.

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