Matches in SemOpenAlex for { <https://semopenalex.org/work/W2116798667> ?p ?o ?g. }
- W2116798667 abstract "Bone and joint problems in Parkinson's disease (PD) are manifold: decreased mobility, abnormal posture, as well as the risk of falling may cause both acute and chronic damage to the musculoskeletal system. In patients with Parkinson's disease, postural instability and falls are frequently observed. The aim of the study was to review the literature with respect to the bone health and risk of fractures in these patients.We conducted a review on bone health in patients with Parkinson's disease.There is evidence that patients with PD have an increased risk of fractures, especially of the hip, due to the elevated risk of falling. While rigidity, bradykinesia and postural instability (but not tremor) predict falls, fractures also correlate with bone mineral density, which is generally lowered in this group of patients as compared to age- and sex-matched controls. Typically PD patients have high turnover osteoporosis due to several causes.Any newly diagnosed patient with PD should be evaluated for the risk of falling and osteoporosis and routinely be supplemented with vitamin D. In the case of osteoporosis, blood samples for detecting underlying and treatable conditions should be taken and bisphosphonates administered to the patient. It is unclear whether drugs typically used for PD provoke or worsen osteoporosis. Nevertheless, every long-term medication should undergo safety studies to demonstrate lack of negative interference with bone metabolism. Drug admission authorities should demand these data when registering new substances or when renewing old admissions." @default.
- W2116798667 created "2016-06-24" @default.
- W2116798667 creator A5020709796 @default.
- W2116798667 creator A5063806503 @default.
- W2116798667 creator A5078479845 @default.
- W2116798667 date "2011-02-16" @default.
- W2116798667 modified "2023-10-17" @default.
- W2116798667 title "Parkinson's disease and the bones" @default.
- W2116798667 cites W131540282 @default.
- W2116798667 cites W1514597511 @default.
- W2116798667 cites W1525779636 @default.
- W2116798667 cites W1550043743 @default.
- W2116798667 cites W1577857118 @default.
- W2116798667 cites W1637454995 @default.
- W2116798667 cites W1933216193 @default.
- W2116798667 cites W1953152576 @default.
- W2116798667 cites W1969341878 @default.
- W2116798667 cites W1969611215 @default.
- W2116798667 cites W1970430331 @default.
- W2116798667 cites W1972973041 @default.
- W2116798667 cites W1976942305 @default.
- W2116798667 cites W1977220229 @default.
- W2116798667 cites W1977301501 @default.
- W2116798667 cites W1978270796 @default.
- W2116798667 cites W1979689847 @default.
- W2116798667 cites W1980525132 @default.
- W2116798667 cites W1982315280 @default.
- W2116798667 cites W1983328252 @default.
- W2116798667 cites W1984221973 @default.
- W2116798667 cites W1988269434 @default.
- W2116798667 cites W1988329144 @default.
- W2116798667 cites W1990676577 @default.
- W2116798667 cites W1995974776 @default.
- W2116798667 cites W1997012068 @default.
- W2116798667 cites W1998497087 @default.
- W2116798667 cites W1999018495 @default.
- W2116798667 cites W2000517652 @default.
- W2116798667 cites W2004329345 @default.
- W2116798667 cites W2004419157 @default.
- W2116798667 cites W2010419468 @default.
- W2116798667 cites W2016151434 @default.
- W2116798667 cites W2023005276 @default.
- W2116798667 cites W2025005764 @default.
- W2116798667 cites W2026465189 @default.
- W2116798667 cites W2027305780 @default.
- W2116798667 cites W2029650656 @default.
- W2116798667 cites W2031041233 @default.
- W2116798667 cites W2038045371 @default.
- W2116798667 cites W2038189911 @default.
- W2116798667 cites W2039158155 @default.
- W2116798667 cites W2039826286 @default.
- W2116798667 cites W2040851961 @default.
- W2116798667 cites W2044780622 @default.
- W2116798667 cites W2046034862 @default.
- W2116798667 cites W2048392109 @default.
- W2116798667 cites W2048546795 @default.
- W2116798667 cites W2050990075 @default.
- W2116798667 cites W2051565231 @default.
- W2116798667 cites W2057983179 @default.
- W2116798667 cites W2059119386 @default.
- W2116798667 cites W2060872414 @default.
- W2116798667 cites W2060977663 @default.
- W2116798667 cites W2063865153 @default.
- W2116798667 cites W2068270634 @default.
- W2116798667 cites W2074297835 @default.
- W2116798667 cites W2074569252 @default.
- W2116798667 cites W2078749465 @default.
- W2116798667 cites W2078749671 @default.
- W2116798667 cites W2081509710 @default.
- W2116798667 cites W2082859231 @default.
- W2116798667 cites W2084447638 @default.
- W2116798667 cites W2086769395 @default.
- W2116798667 cites W2089029145 @default.
- W2116798667 cites W2089141705 @default.
- W2116798667 cites W2090288964 @default.
- W2116798667 cites W2090973045 @default.
- W2116798667 cites W2095512225 @default.
- W2116798667 cites W2095866838 @default.
- W2116798667 cites W2099007490 @default.
- W2116798667 cites W2101076802 @default.
- W2116798667 cites W2101663439 @default.
- W2116798667 cites W2105182594 @default.
- W2116798667 cites W2106026803 @default.
- W2116798667 cites W2108987128 @default.
- W2116798667 cites W2116865613 @default.
- W2116798667 cites W2120261841 @default.
- W2116798667 cites W2124822907 @default.
- W2116798667 cites W2128290688 @default.
- W2116798667 cites W2129240684 @default.
- W2116798667 cites W2139900098 @default.
- W2116798667 cites W2142366479 @default.
- W2116798667 cites W2142471806 @default.
- W2116798667 cites W2144717748 @default.
- W2116798667 cites W2144930923 @default.
- W2116798667 cites W2145582821 @default.
- W2116798667 cites W2148927972 @default.
- W2116798667 cites W2149732522 @default.
- W2116798667 cites W2151189936 @default.
- W2116798667 cites W2166562076 @default.
- W2116798667 cites W2167359851 @default.