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- W2116832014 abstract "In this paper, we describe a miniaturised image-based fluorescence detection system and demonstrate its viability as a highly sensitive tool for point-of-care-analysis of drugs of abuse in human sweat with a focus on monitor individuals for drugs of abuse. Investigations of miniaturised and low power optoelectronic configurations and methodologies for real-time image analysis were successfully carried out. The miniaturised fluorescence detection system was validated against a reference detection system under controlled laboratory conditions by analysing spiked sweat samples in dip stick and then strip with sample pad. As a result of the validation studies, a 1 ng mL−1 limit of detection of cocaine in sweat and full agreement of test results with the reference detection system can be reported. Results of the investigations open the way towards a detection system that integrates a hand-held fluorescence reader and a wearable skinpatch, and which can collect and in situ analyse sweat for the presence of cocaine at any point for up to tenths hours." @default.
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- W2116832014 date "2015-07-16" @default.
- W2116832014 modified "2023-09-26" @default.
- W2116832014 title "A miniaturised image based fluorescence detection system for point-of-care-testing of cocaine abuse" @default.
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- W2116832014 doi "https://doi.org/10.1088/0957-0233/26/8/085401" @default.
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