FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2116859403> ?p ?o ?g. }

• W2116859403 endingPage "721" @default.
• W2116859403 startingPage "715" @default.
• W2116859403 abstract "Salivary dysfunction and oral disorders have been described in both type 1 and type 2 diabetes mellitus. However, the cellular and molecular consequences of diabetes on oral tissues remain to be ascertained. The purpose of this investigation was to study, by means of electron microscopy, the morphologic and molecular changes that occur in salivary glands during diabetes.Biopsy samples of parotid glands were excised from non-diabetic and diabetic (type 1 and type 2) consenting patients and processed by standard methods for routine morphology and electron microscopic immunogold labeling. Specific antibodies were used to determine and quantify the expression of secretory proteins (alphaamylase and the regulatory subunit of type II protein kinase A).Morphologic changes in the diabetic samples included increased numbers of secretory granules, and alterations in internal granule structure. Quantitative analysis of immunogold labeling showed that labeling densities were variable among the parotid gland samples. In type 1 diabetes amylase expression was greater than in non-diabetic glands, whereas in type 2 diabetes it was not significantly changed. Expression of type II regulatory subunits was slightly, although not significantly, increased in acinar secretory granules of type 1 diabetic samples and was unchanged in type 2 diabetic samples.Our data show that diabetes elicits specific changes in secretory protein expression in human salivary glands, thus contributing to the altered oral environment and oral disease associated with diabetes." @default.
• W2116859403 created "2016-06-24" @default.
• W2116859403 creator A5000383095 @default.
• W2116859403 creator A5007296483 @default.
• W2116859403 creator A5077140385 @default.
• W2116859403 creator A5089124699 @default.
• W2116859403 date "2010-04-29" @default.
• W2116859403 modified "2023-10-15" @default.
• W2116859403 title "Amylase and cyclic amp receptor protein expression in human diabetic parotid glands" @default.
• W2116859403 cites W1944789111 @default.
• W2116859403 cites W1946050661 @default.
• W2116859403 cites W1974703242 @default.
• W2116859403 cites W1979492252 @default.
• W2116859403 cites W1984439119 @default.
• W2116859403 cites W1984738218 @default.
• W2116859403 cites W2000696204 @default.
• W2116859403 cites W2007576281 @default.
• W2116859403 cites W2009670540 @default.
• W2116859403 cites W2017479841 @default.
• W2116859403 cites W2019933157 @default.
• W2116859403 cites W2029722018 @default.
• W2116859403 cites W2029849099 @default.
• W2116859403 cites W2032500627 @default.
• W2116859403 cites W2033037565 @default.
• W2116859403 cites W2038680180 @default.
• W2116859403 cites W2051636868 @default.
• W2116859403 cites W2056705275 @default.
• W2116859403 cites W2058990297 @default.
• W2116859403 cites W2060406163 @default.
• W2116859403 cites W2060757769 @default.
• W2116859403 cites W2061301258 @default.
• W2116859403 cites W2067926833 @default.
• W2116859403 cites W2070063735 @default.
• W2116859403 cites W2071009065 @default.
• W2116859403 cites W2076196594 @default.
• W2116859403 cites W2077970957 @default.
• W2116859403 cites W2078364806 @default.
• W2116859403 cites W2083214965 @default.
• W2116859403 cites W2083421259 @default.
• W2116859403 cites W2088944152 @default.
• W2116859403 cites W2096985228 @default.
• W2116859403 cites W2098596446 @default.
• W2116859403 cites W2103916827 @default.
• W2116859403 cites W2113961762 @default.
• W2116859403 cites W2114891343 @default.
• W2116859403 cites W2117297215 @default.
• W2116859403 cites W2117909097 @default.
• W2116859403 cites W2125877331 @default.
• W2116859403 cites W2126567206 @default.
• W2116859403 cites W2146550728 @default.
• W2116859403 cites W2149477363 @default.
• W2116859403 cites W2166811167 @default.
• W2116859403 cites W2398421528 @default.
• W2116859403 cites W4293301989 @default.
• W2116859403 doi "https://doi.org/10.1111/j.1600-0714.2010.00898.x" @default.
• W2116859403 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20456617" @default.
• W2116859403 hasPublicationYear "2010" @default.
• W2116859403 type Work @default.
• W2116859403 sameAs 2116859403 @default.
• W2116859403 citedByCount "23" @default.
• W2116859403 countsByYear W21168594032012 @default.
• W2116859403 countsByYear W21168594032013 @default.
• W2116859403 countsByYear W21168594032014 @default.
• W2116859403 countsByYear W21168594032015 @default.
• W2116859403 countsByYear W21168594032016 @default.
• W2116859403 countsByYear W21168594032017 @default.
• W2116859403 countsByYear W21168594032018 @default.
• W2116859403 countsByYear W21168594032019 @default.
• W2116859403 countsByYear W21168594032020 @default.
• W2116859403 countsByYear W21168594032021 @default.
• W2116859403 countsByYear W21168594032022 @default.
• W2116859403 crossrefType "journal-article" @default.
• W2116859403 hasAuthorship W2116859403A5000383095 @default.
• W2116859403 hasAuthorship W2116859403A5007296483 @default.
• W2116859403 hasAuthorship W2116859403A5077140385 @default.
• W2116859403 hasAuthorship W2116859403A5089124699 @default.
• W2116859403 hasConcept C126322002 @default.
• W2116859403 hasConcept C134018914 @default.
• W2116859403 hasConcept C142724271 @default.
• W2116859403 hasConcept C156399914 @default.
• W2116859403 hasConcept C159654299 @default.
• W2116859403 hasConcept C170835558 @default.
• W2116859403 hasConcept C181199279 @default.
• W2116859403 hasConcept C203014093 @default.
• W2116859403 hasConcept C2777180221 @default.
• W2116859403 hasConcept C2778937882 @default.
• W2116859403 hasConcept C2780395140 @default.
• W2116859403 hasConcept C30030713 @default.
• W2116859403 hasConcept C49039625 @default.
• W2116859403 hasConcept C504460877 @default.
• W2116859403 hasConcept C55493867 @default.
• W2116859403 hasConcept C555293320 @default.
• W2116859403 hasConcept C71924100 @default.
• W2116859403 hasConcept C86803240 @default.
• W2116859403 hasConceptScore W2116859403C126322002 @default.
• W2116859403 hasConceptScore W2116859403C134018914 @default.
• W2116859403 hasConceptScore W2116859403C142724271 @default.
• W2116859403 hasConceptScore W2116859403C156399914 @default.

• next