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- W2116957620 endingPage "304" @default.
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- W2116957620 abstract "ABSTRACT Prognosis of patients with advanced hepatocellular carcinoma (HCC) is poor and is largely influenced by associated liver comorbidities. Moreover, effective treatment alternatives are limited; with the exception of the multitargeted inhibitor sorafenib, established options in the treatment of advanced HCC no longer amenable with ablative or locoregional procedures are lacking. In light of the limited efficacy of chemotherapy in this setting, great efforts have been made in the definition of targetable molecular pathways with a central role in the progression of HCC. Targeting angiogenesis, growth factor receptors, intracellular transduction pathways, or mechanisms of gene-expression regulation represents the main way to improve patient outcome. At the same time, identifying clinical and biological factors, which may help selecting patients with higher chances of benefit, is essential in order to hasten drug development and maximize treatment efficacy." @default.
- W2116957620 created "2016-06-24" @default.
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- W2116957620 date "2014-02-01" @default.
- W2116957620 modified "2023-10-04" @default.
- W2116957620 title "Dissecting signaling pathways in hepatocellular carcinoma: new perspectives in medical therapy" @default.
- W2116957620 cites W1521700858 @default.
- W2116957620 cites W1524978969 @default.
- W2116957620 cites W1783715369 @default.
- W2116957620 cites W1965262464 @default.
- W2116957620 cites W1965309017 @default.
- W2116957620 cites W1966357284 @default.
- W2116957620 cites W1967657141 @default.
- W2116957620 cites W1968209756 @default.
- W2116957620 cites W1971837077 @default.
- W2116957620 cites W1978514461 @default.
- W2116957620 cites W1984322505 @default.
- W2116957620 cites W1990459651 @default.
- W2116957620 cites W1994193851 @default.
- W2116957620 cites W1995690335 @default.
- W2116957620 cites W1995811009 @default.
- W2116957620 cites W1998976242 @default.
- W2116957620 cites W1999827791 @default.
- W2116957620 cites W2009487494 @default.
- W2116957620 cites W2012222876 @default.
- W2116957620 cites W2016364458 @default.
- W2116957620 cites W2017322644 @default.
- W2116957620 cites W2017687774 @default.
- W2116957620 cites W2020509813 @default.
- W2116957620 cites W2022059412 @default.
- W2116957620 cites W2022665891 @default.
- W2116957620 cites W2023447208 @default.
- W2116957620 cites W2028525116 @default.
- W2116957620 cites W2029444490 @default.
- W2116957620 cites W2033172978 @default.
- W2116957620 cites W2038625523 @default.
- W2116957620 cites W2042571415 @default.
- W2116957620 cites W2046000826 @default.
- W2116957620 cites W2051684210 @default.
- W2116957620 cites W2052730188 @default.
- W2116957620 cites W2068735668 @default.
- W2116957620 cites W2068834940 @default.
- W2116957620 cites W2073025925 @default.
- W2116957620 cites W2073165102 @default.
- W2116957620 cites W2074137258 @default.
- W2116957620 cites W2080663543 @default.
- W2116957620 cites W2085547877 @default.
- W2116957620 cites W2089449278 @default.
- W2116957620 cites W2092888413 @default.
- W2116957620 cites W2093059993 @default.
- W2116957620 cites W2097373408 @default.
- W2116957620 cites W2099657378 @default.
- W2116957620 cites W2100297634 @default.
- W2116957620 cites W2100545636 @default.
- W2116957620 cites W2101624426 @default.
- W2116957620 cites W2103119762 @default.
- W2116957620 cites W2106036268 @default.
- W2116957620 cites W2109746877 @default.
- W2116957620 cites W2113222623 @default.
- W2116957620 cites W2115157373 @default.
- W2116957620 cites W2115497785 @default.
- W2116957620 cites W2116922255 @default.
- W2116957620 cites W2119242310 @default.
- W2116957620 cites W2121917437 @default.
- W2116957620 cites W2126427849 @default.
- W2116957620 cites W2127151069 @default.
- W2116957620 cites W2129802218 @default.
- W2116957620 cites W2130210996 @default.
- W2116957620 cites W2132215313 @default.
- W2116957620 cites W2133559579 @default.
- W2116957620 cites W2136745780 @default.
- W2116957620 cites W2136977965 @default.
- W2116957620 cites W2137052325 @default.
- W2116957620 cites W2140587309 @default.
- W2116957620 cites W2145271725 @default.
- W2116957620 cites W2145803146 @default.
- W2116957620 cites W2146781227 @default.
- W2116957620 cites W2147834058 @default.
- W2116957620 cites W2156012497 @default.
- W2116957620 cites W2157535532 @default.
- W2116957620 cites W2157803975 @default.
- W2116957620 cites W2162242700 @default.
- W2116957620 cites W2165901246 @default.
- W2116957620 cites W2166805191 @default.
- W2116957620 cites W2167597760 @default.
- W2116957620 cites W2228442267 @default.
- W2116957620 cites W2241609366 @default.
- W2116957620 cites W2291498461 @default.
- W2116957620 cites W2415622717 @default.