FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2116958494> ?p ?o ?g. }

• W2116958494 endingPage "18" @default.
• W2116958494 startingPage "9" @default.
• W2116958494 abstract "Intra-nigral administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) caused a lesion in the substantia nigra, compact part (SNc) and a specific loss of dopamine and its metabolites in the striatum of rats. The animals were then tested in the two-way active avoidance task. MPTP-treated animals presented lower learning scores in the training and test sessions, an effect that was not caused by motor impairment or by a decreased sensitivity to footshock since their reaction time to the footshock (unconditioned stimulus - UCS) was not reduced. These lower scores were also not attributable to lower acoustic sensitivity or to a slowing in the association of the sound cue (conditioned stimulus - CS) with the UCS since the reaction time to the CS in the active avoidance response did not differ between MPTP-treated and control groups. Therefore, these results are more properly attributable to an impairment of the memory acquisition and retention processes. In addition, this study is presented as a model of early Parkinson's Disease amnesia and is discussed in terms of the importance of the nigrostriatal pathway to memory acquisition and storage processes." @default.
• W2116958494 created "2016-06-24" @default.
• W2116958494 creator A5015170484 @default.
• W2116958494 creator A5025599160 @default.
• W2116958494 creator A5049490216 @default.
• W2116958494 creator A5055640077 @default.
• W2116958494 creator A5066059649 @default.
• W2116958494 creator A5076025989 @default.
• W2116958494 creator A5077864974 @default.
• W2116958494 creator A5081635107 @default.
• W2116958494 date "2001-09-28" @default.
• W2116958494 modified "2023-10-18" @default.
• W2116958494 title "Memory disruption in rats with nigral lesions induced by MPTP: a model for early Parkinson's disease amnesia" @default.
• W2116958494 cites W1161607462 @default.
• W2116958494 cites W136073532 @default.
• W2116958494 cites W147524313 @default.
• W2116958494 cites W1483439847 @default.
• W2116958494 cites W1540086863 @default.
• W2116958494 cites W1586318501 @default.
• W2116958494 cites W1589605243 @default.
• W2116958494 cites W1759162153 @default.
• W2116958494 cites W1967530679 @default.
• W2116958494 cites W1969275478 @default.
• W2116958494 cites W1978528211 @default.
• W2116958494 cites W1979482385 @default.
• W2116958494 cites W1981574170 @default.
• W2116958494 cites W1987320417 @default.
• W2116958494 cites W1988168915 @default.
• W2116958494 cites W1991318104 @default.
• W2116958494 cites W1991702917 @default.
• W2116958494 cites W1992715287 @default.
• W2116958494 cites W1994348655 @default.
• W2116958494 cites W1996552582 @default.
• W2116958494 cites W1996809611 @default.
• W2116958494 cites W1999580412 @default.
• W2116958494 cites W2005264554 @default.
• W2116958494 cites W2006230427 @default.
• W2116958494 cites W2006454374 @default.
• W2116958494 cites W2008274305 @default.
• W2116958494 cites W2008316985 @default.
• W2116958494 cites W2009021103 @default.
• W2116958494 cites W2010206955 @default.
• W2116958494 cites W2010983016 @default.
• W2116958494 cites W2012130528 @default.
• W2116958494 cites W2014089188 @default.
• W2116958494 cites W2017084560 @default.
• W2116958494 cites W2022593245 @default.
• W2116958494 cites W2024854772 @default.
• W2116958494 cites W2027442595 @default.
• W2116958494 cites W2027591104 @default.
• W2116958494 cites W2028391633 @default.
• W2116958494 cites W2031852956 @default.
• W2116958494 cites W2032512623 @default.
• W2116958494 cites W2033080466 @default.
• W2116958494 cites W2034919334 @default.
• W2116958494 cites W2038052392 @default.
• W2116958494 cites W2039064184 @default.
• W2116958494 cites W2039518253 @default.
• W2116958494 cites W2039904991 @default.
• W2116958494 cites W2043158632 @default.
• W2116958494 cites W2045964282 @default.
• W2116958494 cites W2048734012 @default.
• W2116958494 cites W2048953131 @default.
• W2116958494 cites W2050693936 @default.
• W2116958494 cites W2051291336 @default.
• W2116958494 cites W2052022378 @default.
• W2116958494 cites W2053467442 @default.
• W2116958494 cites W2054421268 @default.
• W2116958494 cites W2059290631 @default.
• W2116958494 cites W2060894317 @default.
• W2116958494 cites W2061067248 @default.
• W2116958494 cites W2061068505 @default.
• W2116958494 cites W2062396165 @default.
• W2116958494 cites W2064559953 @default.
• W2116958494 cites W2065364720 @default.
• W2116958494 cites W2069642809 @default.
• W2116958494 cites W2071111270 @default.
• W2116958494 cites W2072062678 @default.
• W2116958494 cites W2073507859 @default.
• W2116958494 cites W2075779864 @default.
• W2116958494 cites W2085001868 @default.
• W2116958494 cites W2085600907 @default.
• W2116958494 cites W2091640069 @default.
• W2116958494 cites W2099652807 @default.
• W2116958494 cites W2111933814 @default.
• W2116958494 cites W2127223684 @default.
• W2116958494 cites W2130069044 @default.
• W2116958494 cites W2147986809 @default.
• W2116958494 cites W2149798376 @default.
• W2116958494 cites W2164398262 @default.
• W2116958494 cites W2169622817 @default.
• W2116958494 cites W2221797639 @default.
• W2116958494 cites W2265949235 @default.
• W2116958494 cites W2399901545 @default.
• W2116958494 cites W2402410749 @default.
• W2116958494 cites W2441941064 @default.
• W2116958494 cites W2495029580 @default.
• W2116958494 cites W2468818892 @default.

• next