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- W2116986306 abstract "Cysteinyl-leukotrienes (cys-LTs, LTC4, LTD4,and LTE4) are potent lipid mediators, resulting from the oxidative metabolism of arachidonic acid through the 5-lipoxygenase (5-LO) pathway. They are able to affect all major components of the cardiovascular system: they can constrict small and large vessels, modify cardiac and coronary functions, influence the microcirculation and contribute to the manifestations of ischaemia/reperfusion injury1,2. Furthermore cys-LTs are able to induce profound modification of vascular permeability, leading to oedema formation3." @default.
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- W2116986306 date "2000-02-01" @default.
- W2116986306 modified "2023-10-17" @default.
- W2116986306 title "Leukotrienes in Cardiovascular Diseases" @default.
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- W2116986306 doi "https://doi.org/10.1164/ajrccm.161.supplement_1.ltta-22" @default.
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