FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2117000551> ?p ?o ?g. }

• W2117000551 endingPage "1318" @default.
• W2117000551 startingPage "1312" @default.
• W2117000551 abstract "Measurements of total and free testosterone levels in women have lacked precision and accuracy because of limited assay sensitivity. The paucity of normative data on total and free testosterone levels in healthy women has confounded interpretation of androgen levels in women with human immunodeficiency virus (HIV) infection and other disease states. Therefore, the objectives of this study were to develop sensitive assays for the measurement of the low total and free testosterone levels in women to define the range for these hormones during the normal menstrual cycle and assess the total and free testosterone levels in HIV-infected women. By using a larger volume of serum, increasing the incubation time, and reducing the antibody concentration, the sensitivity of the total testosterone assay was increased to 0.008 nmol/L, and that of the free testosterone assay was increased to 2 pmol/L. The mean percent free testosterone was 1.0 +/- 0.1% of the total testosterone. Serum total and free testosterone levels in the follicular and luteal phases were not significantly different, but both demonstrated a modest preovulatory increase, 3 days before the LH peak. Serum total [0.50 +/- 0.32 (14.60 +/- 9.22) vs. 1.2 +/- 0.7 nmol/L (34.3 +/- 21.0 ng/dL); P < 0.0001] and free testosterone levels (5.56 +/- 2.70 (1.58 +/- 0.80) vs. 12.8 +/- 5.5 pmol/L (3.4 +/- 1.7 pg/mL); P < 0.0001) were significantly lower in HIV-infected women (n = 37) than in healthy women (n = 34). Serum total and free testosterone levels were also significantly lower in HIV-infected women who were menstruating normally. There were no significant differences in serum total and free testosterone levels between those who had lost weight and those who had not. Testosterone levels correlated inversely with plasma HIV ribonucleic acid copy number. Serum FSH, but not LH, levels were significantly higher in HIV-infected women than in controls. Using assays with sufficient sensitivity, we defined the range for total and free testosterone levels during the normal menstrual cycle. Serum total and free testosterone levels are lower in HIV-infected women and correlate inversely with plasma HIV ribonucleic acid levels. The hypothesis that androgen deficiency contributes to wasting in HIV-infected women remains to be tested." @default.
• W2117000551 created "2016-06-24" @default.
• W2117000551 creator A5009773473 @default.
• W2117000551 creator A5050191711 @default.
• W2117000551 creator A5057103869 @default.
• W2117000551 creator A5058875385 @default.
• W2117000551 creator A5060819068 @default.
• W2117000551 creator A5071176339 @default.
• W2117000551 creator A5072086085 @default.
• W2117000551 creator A5073133811 @default.
• W2117000551 creator A5073876851 @default.
• W2117000551 creator A5077852476 @default.
• W2117000551 creator A5089053900 @default.
• W2117000551 date "1998-04-01" @default.
• W2117000551 modified "2023-10-13" @default.
• W2117000551 title "The Use of a Sensitive Equilibrium Dialysis Method for the Measurement of Free Testosterone Levels in Healthy, Cycling Women and in Human Immunodeficiency Virus-Infected Women1" @default.
• W2117000551 cites W1480200412 @default.
• W2117000551 cites W1517007955 @default.
• W2117000551 cites W1914859814 @default.
• W2117000551 cites W1974522380 @default.
• W2117000551 cites W1974568933 @default.
• W2117000551 cites W1977757546 @default.
• W2117000551 cites W1980352939 @default.
• W2117000551 cites W1985592735 @default.
• W2117000551 cites W1986692022 @default.
• W2117000551 cites W1988006102 @default.
• W2117000551 cites W1989247380 @default.
• W2117000551 cites W1992620392 @default.
• W2117000551 cites W1995228363 @default.
• W2117000551 cites W2022211093 @default.
• W2117000551 cites W2023090433 @default.
• W2117000551 cites W2027586930 @default.
• W2117000551 cites W2029068660 @default.
• W2117000551 cites W2029075686 @default.
• W2117000551 cites W2036173424 @default.
• W2117000551 cites W2038162032 @default.
• W2117000551 cites W2045278103 @default.
• W2117000551 cites W2048574324 @default.
• W2117000551 cites W2050484836 @default.
• W2117000551 cites W2053216237 @default.
• W2117000551 cites W2071297758 @default.
• W2117000551 cites W2073209871 @default.
• W2117000551 cites W2077017506 @default.
• W2117000551 cites W2078986406 @default.
• W2117000551 cites W2079582382 @default.
• W2117000551 cites W2082662520 @default.
• W2117000551 cites W2093863215 @default.
• W2117000551 cites W2096860470 @default.
• W2117000551 cites W2097914285 @default.
• W2117000551 cites W2106601653 @default.
• W2117000551 cites W2107541080 @default.
• W2117000551 cites W2117231350 @default.
• W2117000551 cites W2118523099 @default.
• W2117000551 cites W2134937898 @default.
• W2117000551 cites W2139906326 @default.
• W2117000551 cites W2145141579 @default.
• W2117000551 cites W2149547682 @default.
• W2117000551 cites W2165818081 @default.
• W2117000551 cites W2185952775 @default.
• W2117000551 cites W2272293150 @default.
• W2117000551 cites W2326289669 @default.
• W2117000551 cites W2338387330 @default.
• W2117000551 cites W2340280382 @default.
• W2117000551 cites W2400835419 @default.
• W2117000551 cites W2407205928 @default.
• W2117000551 cites W2418198155 @default.
• W2117000551 cites W2463621402 @default.
• W2117000551 doi "https://doi.org/10.1210/jcem.83.4.4718" @default.
• W2117000551 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9543161" @default.
• W2117000551 hasPublicationYear "1998" @default.
• W2117000551 type Work @default.
• W2117000551 sameAs 2117000551 @default.
• W2117000551 citedByCount "72" @default.
• W2117000551 countsByYear W21170005512012 @default.
• W2117000551 countsByYear W21170005512013 @default.
• W2117000551 countsByYear W21170005512014 @default.
• W2117000551 countsByYear W21170005512015 @default.
• W2117000551 countsByYear W21170005512016 @default.
• W2117000551 countsByYear W21170005512018 @default.
• W2117000551 countsByYear W21170005512019 @default.
• W2117000551 countsByYear W21170005512021 @default.
• W2117000551 countsByYear W21170005512022 @default.
• W2117000551 crossrefType "journal-article" @default.
• W2117000551 hasAuthorship W2117000551A5009773473 @default.
• W2117000551 hasAuthorship W2117000551A5050191711 @default.
• W2117000551 hasAuthorship W2117000551A5057103869 @default.
• W2117000551 hasAuthorship W2117000551A5058875385 @default.
• W2117000551 hasAuthorship W2117000551A5060819068 @default.
• W2117000551 hasAuthorship W2117000551A5071176339 @default.
• W2117000551 hasAuthorship W2117000551A5072086085 @default.
• W2117000551 hasAuthorship W2117000551A5073133811 @default.
• W2117000551 hasAuthorship W2117000551A5073876851 @default.
• W2117000551 hasAuthorship W2117000551A5077852476 @default.
• W2117000551 hasAuthorship W2117000551A5089053900 @default.
• W2117000551 hasBestOaLocation W21170005511 @default.
• W2117000551 hasConcept C126322002 @default.
• W2117000551 hasConcept C134018914 @default.
• W2117000551 hasConcept C143228043 @default.

• next