Matches in SemOpenAlex for { <https://semopenalex.org/work/W2117089445> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2117089445 endingPage "346" @default.
- W2117089445 startingPage "341" @default.
- W2117089445 abstract "A thymidine kinase (TK), inverted repeat, glycoprotein I (gI) and glycoprotein X (gpX) gene-deleted modified live virus pseudorabies vaccine was evaluated for safety in swine and for efficacy in protecting swine against challenge with pseudorabies virus (PRV). Safety was evaluated by inoculating pregnant gilts intravenously and 3-day-old pigs intracerebrally with the vaccine. Efficacy was evaluated by 1) vaccinating 3-day-old pigs with a minimal protective dose intranasally and then challenging with PRV 3 weeks postvaccination or 2) vaccinating weaned pigs with a standard field dose intramuscularly and then challenging with PRV 4 weeks postvaccination. The pigs vaccinated intranasally remained clinically normal following vaccination and challenge with PRV. The pigs vaccinated intramuscularly remained clinically normal following vaccination, but mild respiratory signs were seen in some of the vaccinated pigs following challenge with PRV. Humoral immune response was evaluated with enzyme-linked immunosorbent assays (ELISAs) and a serum virus neutralization test. All of the intramuscularly vaccinated pigs became gI and gpX positive on differential ELISAs following challenge. All of the intranasally vaccinated pigs were seropositive on the indirect gI ELISA following challenge, but not all of the pigs were seropositive on the blocking gI ELISA or the gpX ELISA 3 weeks postchallenge." @default.
- W2117089445 created "2016-06-24" @default.
- W2117089445 creator A5032121719 @default.
- W2117089445 creator A5065630185 @default.
- W2117089445 creator A5067879535 @default.
- W2117089445 date "1993-07-01" @default.
- W2117089445 modified "2023-10-17" @default.
- W2117089445 title "Evaluation of the Safety and Efficacy of a Thymidine Kinase, Inverted Repeat, gI, and gpX Gene-Deleted Pseudorabies Vaccine" @default.
- W2117089445 cites W1504704761 @default.
- W2117089445 cites W1632503918 @default.
- W2117089445 cites W1969071735 @default.
- W2117089445 cites W2003753899 @default.
- W2117089445 cites W2077328229 @default.
- W2117089445 cites W2090408847 @default.
- W2117089445 cites W2095027340 @default.
- W2117089445 cites W2104010262 @default.
- W2117089445 cites W2106133768 @default.
- W2117089445 cites W2140425913 @default.
- W2117089445 cites W2328962670 @default.
- W2117089445 doi "https://doi.org/10.1177/104063879300500306" @default.
- W2117089445 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8396983" @default.
- W2117089445 hasPublicationYear "1993" @default.
- W2117089445 type Work @default.
- W2117089445 sameAs 2117089445 @default.
- W2117089445 citedByCount "10" @default.
- W2117089445 countsByYear W21170894452012 @default.
- W2117089445 countsByYear W21170894452016 @default.
- W2117089445 countsByYear W21170894452017 @default.
- W2117089445 countsByYear W21170894452019 @default.
- W2117089445 countsByYear W21170894452023 @default.
- W2117089445 crossrefType "journal-article" @default.
- W2117089445 hasAuthorship W2117089445A5032121719 @default.
- W2117089445 hasAuthorship W2117089445A5065630185 @default.
- W2117089445 hasAuthorship W2117089445A5067879535 @default.
- W2117089445 hasBestOaLocation W21170894451 @default.
- W2117089445 hasConcept C159047783 @default.
- W2117089445 hasConcept C203014093 @default.
- W2117089445 hasConcept C22070199 @default.
- W2117089445 hasConcept C2522874641 @default.
- W2117089445 hasConcept C2775976905 @default.
- W2117089445 hasConcept C2776147627 @default.
- W2117089445 hasConcept C2776409557 @default.
- W2117089445 hasConcept C2780727368 @default.
- W2117089445 hasConcept C2781092067 @default.
- W2117089445 hasConcept C2781196997 @default.
- W2117089445 hasConcept C71924100 @default.
- W2117089445 hasConcept C85663871 @default.
- W2117089445 hasConceptScore W2117089445C159047783 @default.
- W2117089445 hasConceptScore W2117089445C203014093 @default.
- W2117089445 hasConceptScore W2117089445C22070199 @default.
- W2117089445 hasConceptScore W2117089445C2522874641 @default.
- W2117089445 hasConceptScore W2117089445C2775976905 @default.
- W2117089445 hasConceptScore W2117089445C2776147627 @default.
- W2117089445 hasConceptScore W2117089445C2776409557 @default.
- W2117089445 hasConceptScore W2117089445C2780727368 @default.
- W2117089445 hasConceptScore W2117089445C2781092067 @default.
- W2117089445 hasConceptScore W2117089445C2781196997 @default.
- W2117089445 hasConceptScore W2117089445C71924100 @default.
- W2117089445 hasConceptScore W2117089445C85663871 @default.
- W2117089445 hasIssue "3" @default.
- W2117089445 hasLocation W21170894451 @default.
- W2117089445 hasLocation W21170894452 @default.
- W2117089445 hasOpenAccess W2117089445 @default.
- W2117089445 hasPrimaryLocation W21170894451 @default.
- W2117089445 hasRelatedWork W1955347619 @default.
- W2117089445 hasRelatedWork W199036555 @default.
- W2117089445 hasRelatedWork W2044516952 @default.
- W2117089445 hasRelatedWork W2089253311 @default.
- W2117089445 hasRelatedWork W2133097205 @default.
- W2117089445 hasRelatedWork W2172121343 @default.
- W2117089445 hasRelatedWork W2400516756 @default.
- W2117089445 hasRelatedWork W2408864419 @default.
- W2117089445 hasRelatedWork W2417834132 @default.
- W2117089445 hasRelatedWork W2468325541 @default.
- W2117089445 hasVolume "5" @default.
- W2117089445 isParatext "false" @default.
- W2117089445 isRetracted "false" @default.
- W2117089445 magId "2117089445" @default.
- W2117089445 workType "article" @default.