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- W211709810 abstract "From the flowers of Hemisteptia lyrata Bunge, two flavonoids, apigenin (1) and acacetin (2), were isolated. Their structures were established by UV, one- and two-dimensional NMR, and mass spectroscopic methods. Apigenin showed significant inhibition against mushroom tyrosinase with an IC_50 value of 4.56㎍·ml^-1, and appeared to inhibit the polyphenol oxidase activity of tyrosinase in a competitive manner (K_1=2.5×10 exp (-5) M) when L-tyrosine was used as a substrate, but did not inhibit the melanin production of Streptomyces bikiniensis." @default.
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- W211709810 date "2002-06-16" @default.
- W211709810 modified "2023-09-27" @default.
- W211709810 title "Apigenin, Tyrosinase Inhibitor Isolated from the Flowers of Hemisteptia lyrata Bunge" @default.
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