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• W2117130003 abstract "The graft-versus-leukaemia (GVL) reaction that occurs after allogeneic haematopoietic cell transplantation (HCT) can cure patients with a variety of haematological malignancies. A heightened appreciation of the GVL effect has resulted in the development of reduced intensity transplant approaches, where antitumour effects occur predominantly as a consequence of the transplanted donor immune system. The recent success of these transplants in patients with acute and chronic leukaemias has led to trials investigating for graft-versus-tumour (GVT) effects in patients with treatment-refractory metastatic solid tumours. This review discusses evidence that immune replacement following allogeneic HCT is a potent form of cancer immunotherapy for patients with haematological and non-haematological malignancies." @default.
• W2117130003 created "2016-06-24" @default.
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• W2117130003 date "2003-10-01" @default.
• W2117130003 modified "2023-09-23" @default.
• W2117130003 title "Allogeneic immune replacement as cancer immunotherapy" @default.
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• W2117130003 doi "https://doi.org/10.1517/14712598.3.7.1051" @default.
• W2117130003 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14519070" @default.
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