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• W2117163822 abstract "Endometriosis is a common benign gynaecological disease. Epidemiological studies have demonstrated associations between endometriosis and ovarian cancer. Recent genome-wide association studies of ovarian cancer have identified several single nucleotide polymorphisms (SNPs) in the Basonuclin 2 (BNC2) gene. In this study, we investigated these polymorphism in women with endometriosis.Six SNPs in and upstream of the BNC2 gene (rs3814113, rs4445329, rs10962656, rs12379183, rs10756819 and rs1339552) were investigated using TaqMan allelic discrimination analysis in a Caucasian population (cases: 798, controls: 351). Allelic frequencies were used as main outcome measure.No associations were observed between the analysed SNPs and endometriosis.Our results suggest that the analysed polymorphisms in the BNC2 gene are unlikely to contribute to the previously reported risk of ovarian cancer in women with endometriosis." @default.
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• W2117163822 date "2011-06-04" @default.
• W2117163822 modified "2023-10-06" @default.
• W2117163822 title "Ovarian cancer-associated polymorphisms in the BNC2 gene among women with endometriosis" @default.
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• W2117163822 doi "https://doi.org/10.1093/humrep/der169" @default.
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• W2117163822 hasPublicationYear "2011" @default.
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