FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2117165729> ?p ?o ?g. }

• W2117165729 endingPage "839" @default.
• W2117165729 startingPage "829" @default.
• W2117165729 abstract "Annona cornifolia A. St. -Hil. is a small annual perennial tree found in the Brazilian savannah; their green fruit is popularly used in the treatment of ulcers. The acetogenins isolated from the seeds of Annona cornifolia previously showed to possess antioxidant activity. In continuation of our investigations on the biological activities of acetogenins, four binary mixtures and ten pure adjacent bis-tetrahydrofuran annonaceous acetogenins were evaluated: the cytotoxic (against three human tumor cell lines), antifungal (against Paracoccidioides brasiliensis), trypanocidal (against Trypanosoma cruzi) and leishmanicidal (against Leishmania amazonensis) activities. Acetogenins presented cytotoxic activity confirming their potential use in anti-cancer therapy. Regarding leishmanicidal and trypanocidal activities, an inhibition of 87% of L. amazonensis amastigotes and 100% of T. cruzi amastigotes and trypomastigotes was observed, when tested at the concentration of 20 µg mL–1. Moreover, six acetogenins showed more activity against all the three tested isolates of P. brasiliensis than trimethoprim-sulfamethoxazole, a drug used for treating paracoccidioidomycosis. Thus, acetogenins may be an alternative in treating a number of diseases that have a huge impact on millions of people worldwide. This paper reports for the first time the antifungal, leishmanicidal and trypanocidal activities for these acetogenins." @default.
• W2117165729 created "2016-06-24" @default.
• W2117165729 creator A5010804221 @default.
• W2117165729 creator A5020342341 @default.
• W2117165729 creator A5026451050 @default.
• W2117165729 creator A5027516808 @default.
• W2117165729 creator A5037193500 @default.
• W2117165729 creator A5049939328 @default.
• W2117165729 creator A5063279562 @default.
• W2117165729 creator A5070327709 @default.
• W2117165729 creator A5075051082 @default.
• W2117165729 date "2014-06-01" @default.
• W2117165729 modified "2023-09-27" @default.
• W2117165729 title "In vitro cytotoxic, antifungal, trypanocidal and leishmanicidal activities of acetogenins isolated from Annona cornifolia A. St. -Hil. (Annonaceae)" @default.
• W2117165729 cites W1479952727 @default.
• W2117165729 cites W1565636659 @default.
• W2117165729 cites W1966893287 @default.
• W2117165729 cites W1970613467 @default.
• W2117165729 cites W1984574459 @default.
• W2117165729 cites W1987955954 @default.
• W2117165729 cites W1992580288 @default.
• W2117165729 cites W1994198459 @default.
• W2117165729 cites W1998145996 @default.
• W2117165729 cites W2001936180 @default.
• W2117165729 cites W2002210845 @default.
• W2117165729 cites W2017793989 @default.
• W2117165729 cites W2025307916 @default.
• W2117165729 cites W2030734721 @default.
• W2117165729 cites W2036613147 @default.
• W2117165729 cites W2041800034 @default.
• W2117165729 cites W2071295178 @default.
• W2117165729 cites W2073541525 @default.
• W2117165729 cites W2077154182 @default.
• W2117165729 cites W2084449759 @default.
• W2117165729 cites W2107294966 @default.
• W2117165729 cites W2109890680 @default.
• W2117165729 cites W2125888372 @default.
• W2117165729 cites W2136450392 @default.
• W2117165729 cites W2146957953 @default.
• W2117165729 cites W2155208683 @default.
• W2117165729 cites W2171765967 @default.
• W2117165729 cites W2325565521 @default.
• W2117165729 doi "https://doi.org/10.1590/0001-3765201420130048" @default.
• W2117165729 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30514008" @default.
• W2117165729 hasPublicationYear "2014" @default.
• W2117165729 type Work @default.
• W2117165729 sameAs 2117165729 @default.
• W2117165729 citedByCount "9" @default.
• W2117165729 countsByYear W21171657292016 @default.
• W2117165729 countsByYear W21171657292017 @default.
• W2117165729 countsByYear W21171657292018 @default.
• W2117165729 countsByYear W21171657292019 @default.
• W2117165729 countsByYear W21171657292020 @default.
• W2117165729 countsByYear W21171657292022 @default.
• W2117165729 crossrefType "journal-article" @default.
• W2117165729 hasAuthorship W2117165729A5010804221 @default.
• W2117165729 hasAuthorship W2117165729A5020342341 @default.
• W2117165729 hasAuthorship W2117165729A5026451050 @default.
• W2117165729 hasAuthorship W2117165729A5027516808 @default.
• W2117165729 hasAuthorship W2117165729A5037193500 @default.
• W2117165729 hasAuthorship W2117165729A5049939328 @default.
• W2117165729 hasAuthorship W2117165729A5063279562 @default.
• W2117165729 hasAuthorship W2117165729A5070327709 @default.
• W2117165729 hasAuthorship W2117165729A5075051082 @default.
• W2117165729 hasBestOaLocation W21171657291 @default.
• W2117165729 hasConcept C136764020 @default.
• W2117165729 hasConcept C154317977 @default.
• W2117165729 hasConcept C202751555 @default.
• W2117165729 hasConcept C2777625466 @default.
• W2117165729 hasConcept C2779565439 @default.
• W2117165729 hasConcept C2780303139 @default.
• W2117165729 hasConcept C2780988704 @default.
• W2117165729 hasConcept C2781092759 @default.
• W2117165729 hasConcept C41008148 @default.
• W2117165729 hasConcept C55493867 @default.
• W2117165729 hasConcept C556039675 @default.
• W2117165729 hasConcept C59822182 @default.
• W2117165729 hasConcept C71924100 @default.
• W2117165729 hasConcept C71928629 @default.
• W2117165729 hasConcept C86803240 @default.
• W2117165729 hasConcept C89423630 @default.
• W2117165729 hasConcept C98319499 @default.
• W2117165729 hasConceptScore W2117165729C136764020 @default.
• W2117165729 hasConceptScore W2117165729C154317977 @default.
• W2117165729 hasConceptScore W2117165729C202751555 @default.
• W2117165729 hasConceptScore W2117165729C2777625466 @default.
• W2117165729 hasConceptScore W2117165729C2779565439 @default.
• W2117165729 hasConceptScore W2117165729C2780303139 @default.
• W2117165729 hasConceptScore W2117165729C2780988704 @default.
• W2117165729 hasConceptScore W2117165729C2781092759 @default.
• W2117165729 hasConceptScore W2117165729C41008148 @default.
• W2117165729 hasConceptScore W2117165729C55493867 @default.
• W2117165729 hasConceptScore W2117165729C556039675 @default.
• W2117165729 hasConceptScore W2117165729C59822182 @default.
• W2117165729 hasConceptScore W2117165729C71924100 @default.
• W2117165729 hasConceptScore W2117165729C71928629 @default.
• W2117165729 hasConceptScore W2117165729C86803240 @default.
• W2117165729 hasConceptScore W2117165729C89423630 @default.

• next