FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2117268045> ?p ?o ?g. }

• W2117268045 endingPage "035014" @default.
• W2117268045 startingPage "035014" @default.
• W2117268045 abstract "Conventional airway in vitro models focus upon the function of individual structural cells cultured in a two-dimensional monolayer, with limited three-dimensional (3D) models of the bronchial mucosa. Electrospinning offers an attractive method to produce defined, porous 3D matrices for cell culture. To investigate the effects of fibre diameter on airway epithelial and fibroblast cell growth and functionality, we manipulated the concentration and deposition rate of the non-degradable polymer polyethylene terephthalate to create fibres with diameters ranging from nanometre to micrometre. The nanofibre scaffold closely resembles the basement membrane of the bronchiole mucosal layer, and epithelial cells cultured at the air–liquid interface on this scaffold showed polarized differentiation. The microfibre scaffold mimics the porous sub-mucosal layer of the airway into which lung fibroblast cells showed good penetration. Using these defined electrospinning parameters we created a biphasic scaffold with 3D topography tailored for optimal growth of both cell types. Epithelial and fibroblast cells were co-cultured onto the apical nanofibre phase and the basal microfibre phase respectively, with enhanced epithelial barrier formation observed upon co-culture. This biphasic scaffold provides a novel 3D in vitro platform optimized to mimic the different microenvironments the cells encounter in vivo on which to investigate key airway structural cell interactions in airway diseases such as asthma." @default.
• W2117268045 created "2016-06-24" @default.
• W2117268045 creator A5017947859 @default.
• W2117268045 creator A5019725924 @default.
• W2117268045 creator A5023313534 @default.
• W2117268045 creator A5048320859 @default.
• W2117268045 creator A5064381884 @default.
• W2117268045 creator A5071572427 @default.
• W2117268045 creator A5071752588 @default.
• W2117268045 creator A5085521466 @default.
• W2117268045 date "2014-06-13" @default.
• W2117268045 modified "2023-10-11" @default.
• W2117268045 title "A novel electrospun biphasic scaffold provides optimal three-dimensional topography for <i>in vitro</i> co-culture of airway epithelial and fibroblast cells" @default.
• W2117268045 cites W1564928816 @default.
• W2117268045 cites W1835748585 @default.
• W2117268045 cites W1963492196 @default.
• W2117268045 cites W1964413664 @default.
• W2117268045 cites W1968484490 @default.
• W2117268045 cites W1973369120 @default.
• W2117268045 cites W1977922675 @default.
• W2117268045 cites W1980068631 @default.
• W2117268045 cites W1981463089 @default.
• W2117268045 cites W1990316566 @default.
• W2117268045 cites W1992878536 @default.
• W2117268045 cites W1992998066 @default.
• W2117268045 cites W1994538451 @default.
• W2117268045 cites W1997986066 @default.
• W2117268045 cites W2001231204 @default.
• W2117268045 cites W2001661294 @default.
• W2117268045 cites W2011729352 @default.
• W2117268045 cites W2026632078 @default.
• W2117268045 cites W2029878860 @default.
• W2117268045 cites W2030106405 @default.
• W2117268045 cites W2034620334 @default.
• W2117268045 cites W2037850728 @default.
• W2117268045 cites W2041778199 @default.
• W2117268045 cites W2042776401 @default.
• W2117268045 cites W2046286899 @default.
• W2117268045 cites W2047266588 @default.
• W2117268045 cites W2062461864 @default.
• W2117268045 cites W2066276903 @default.
• W2117268045 cites W2072121454 @default.
• W2117268045 cites W2073374778 @default.
• W2117268045 cites W2080128370 @default.
• W2117268045 cites W2096242114 @default.
• W2117268045 cites W2108373121 @default.
• W2117268045 cites W2108974834 @default.
• W2117268045 cites W2115349187 @default.
• W2117268045 cites W2116397695 @default.
• W2117268045 cites W2117559866 @default.
• W2117268045 cites W2122318059 @default.
• W2117268045 cites W2124154250 @default.
• W2117268045 cites W2124924791 @default.
• W2117268045 cites W2130543588 @default.
• W2117268045 cites W2134257943 @default.
• W2117268045 cites W2136525368 @default.
• W2117268045 cites W2138844071 @default.
• W2117268045 cites W2140410130 @default.
• W2117268045 cites W2141430390 @default.
• W2117268045 cites W2150267721 @default.
• W2117268045 cites W2162490082 @default.
• W2117268045 cites W2163150448 @default.
• W2117268045 cites W2165098074 @default.
• W2117268045 cites W2167091328 @default.
• W2117268045 cites W2726062218 @default.
• W2117268045 cites W4236509867 @default.
• W2117268045 cites W4239898117 @default.
• W2117268045 cites W4295816494 @default.
• W2117268045 cites W95323076 @default.
• W2117268045 doi "https://doi.org/10.1088/1758-5082/6/3/035014" @default.
• W2117268045 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24925127" @default.
• W2117268045 hasPublicationYear "2014" @default.
• W2117268045 type Work @default.
• W2117268045 sameAs 2117268045 @default.
• W2117268045 citedByCount "35" @default.
• W2117268045 countsByYear W21172680452015 @default.
• W2117268045 countsByYear W21172680452016 @default.
• W2117268045 countsByYear W21172680452017 @default.
• W2117268045 countsByYear W21172680452018 @default.
• W2117268045 countsByYear W21172680452019 @default.
• W2117268045 countsByYear W21172680452020 @default.
• W2117268045 countsByYear W21172680452021 @default.
• W2117268045 countsByYear W21172680452022 @default.
• W2117268045 countsByYear W21172680452023 @default.
• W2117268045 crossrefType "journal-article" @default.
• W2117268045 hasAuthorship W2117268045A5017947859 @default.
• W2117268045 hasAuthorship W2117268045A5019725924 @default.
• W2117268045 hasAuthorship W2117268045A5023313534 @default.
• W2117268045 hasAuthorship W2117268045A5048320859 @default.
• W2117268045 hasAuthorship W2117268045A5064381884 @default.
• W2117268045 hasAuthorship W2117268045A5071572427 @default.
• W2117268045 hasAuthorship W2117268045A5071752588 @default.
• W2117268045 hasAuthorship W2117268045A5085521466 @default.
• W2117268045 hasConcept C12554922 @default.
• W2117268045 hasConcept C12820456 @default.
• W2117268045 hasConcept C136229726 @default.
• W2117268045 hasConcept C144796933 @default.
• W2117268045 hasConcept C159985019 @default.

• next