FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2117274465> ?p ?o ?g. }

• W2117274465 endingPage "1116" @default.
• W2117274465 startingPage "1107" @default.
• W2117274465 abstract "Aim: To investigate the unbalance of proliferation and apoptosis and the functions of cell‐cycle proteins and apoptotic factor in metastasis of hepatocellular carcinoma (HCC) and their effect in prognosis. Methods: Proliferation index and apoptosis index, as well as seven relatively molecular markers, namely p15, p34, p53, p57, p73, survivin and nm23, were evaluated by immunohistochemistry and TUNEL in HCC tissues and compared to adjacent non‐cancerous tissues and normal liver tissues. Furthermore, the prognostic significance by follow‐up and mutual relationships for each clinicopathologic factor and molecular marker were analysed. Results: The dysregulation between proliferation and apoptosis and the abnormal expression of seven molecular markers were observed in HCC tissues. The unbalance of proliferation and apoptosis and abnormal expressions of p15, p34, p57 and nm23 were correlated with TNM stage and extrahepatic metastasis. In particular, the abnormal co‐expression of nm23/p57 correlated with advanced TNM stage and bigger tumor size and was an independent prognostic factor of HCC. Conclusion: The unbalance of proliferation and apoptosis and abnormal expression of cell‐cycle proteins promote metastasis of HCC. Moreover, the abnormal co‐expression of nm23/p57 may be a useful molecular marker for metastasis and unfavourable prognosis for HCC." @default.
• W2117274465 created "2016-06-24" @default.
• W2117274465 creator A5003043325 @default.
• W2117274465 creator A5006692249 @default.
• W2117274465 creator A5027459053 @default.
• W2117274465 creator A5029479913 @default.
• W2117274465 creator A5040267650 @default.
• W2117274465 creator A5053284866 @default.
• W2117274465 creator A5075378373 @default.
• W2117274465 creator A5077314806 @default.
• W2117274465 date "2010-09-28" @default.
• W2117274465 modified "2023-10-16" @default.
• W2117274465 title "Prognostic significance of co-expression of nm23 and p57 protein in hepatocellular carcinoma" @default.
• W2117274465 cites W1991938154 @default.
• W2117274465 cites W2007454597 @default.
• W2117274465 cites W2008544109 @default.
• W2117274465 cites W2019473502 @default.
• W2117274465 cites W2020516267 @default.
• W2117274465 cites W2022989272 @default.
• W2117274465 cites W2026004604 @default.
• W2117274465 cites W2032172756 @default.
• W2117274465 cites W2035995888 @default.
• W2117274465 cites W2039065654 @default.
• W2117274465 cites W2041466446 @default.
• W2117274465 cites W2050675108 @default.
• W2117274465 cites W2052976853 @default.
• W2117274465 cites W2058551926 @default.
• W2117274465 cites W2063817436 @default.
• W2117274465 cites W2069526622 @default.
• W2117274465 cites W2071458275 @default.
• W2117274465 cites W2075111888 @default.
• W2117274465 cites W2083731894 @default.
• W2117274465 cites W2086933275 @default.
• W2117274465 cites W2091729097 @default.
• W2117274465 cites W2097711594 @default.
• W2117274465 cites W2119768794 @default.
• W2117274465 cites W2132820802 @default.
• W2117274465 cites W2134548801 @default.
• W2117274465 cites W2147938572 @default.
• W2117274465 cites W2150833831 @default.
• W2117274465 cites W2161818053 @default.
• W2117274465 cites W2463873384 @default.
• W2117274465 doi "https://doi.org/10.1111/j.1872-034x.2010.00721.x" @default.
• W2117274465 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20880063" @default.
• W2117274465 hasPublicationYear "2010" @default.
• W2117274465 type Work @default.
• W2117274465 sameAs 2117274465 @default.
• W2117274465 citedByCount "12" @default.
• W2117274465 countsByYear W21172744652012 @default.
• W2117274465 countsByYear W21172744652016 @default.
• W2117274465 countsByYear W21172744652018 @default.
• W2117274465 countsByYear W21172744652019 @default.
• W2117274465 countsByYear W21172744652022 @default.
• W2117274465 crossrefType "journal-article" @default.
• W2117274465 hasAuthorship W2117274465A5003043325 @default.
• W2117274465 hasAuthorship W2117274465A5006692249 @default.
• W2117274465 hasAuthorship W2117274465A5027459053 @default.
• W2117274465 hasAuthorship W2117274465A5029479913 @default.
• W2117274465 hasAuthorship W2117274465A5040267650 @default.
• W2117274465 hasAuthorship W2117274465A5053284866 @default.
• W2117274465 hasAuthorship W2117274465A5075378373 @default.
• W2117274465 hasAuthorship W2117274465A5077314806 @default.
• W2117274465 hasConcept C121608353 @default.
• W2117274465 hasConcept C126322002 @default.
• W2117274465 hasConcept C142724271 @default.
• W2117274465 hasConcept C146357865 @default.
• W2117274465 hasConcept C151730666 @default.
• W2117274465 hasConcept C190283241 @default.
• W2117274465 hasConcept C196795494 @default.
• W2117274465 hasConcept C204232928 @default.
• W2117274465 hasConcept C2775975398 @default.
• W2117274465 hasConcept C2777751288 @default.
• W2117274465 hasConcept C2778019345 @default.
• W2117274465 hasConcept C2779013556 @default.
• W2117274465 hasConcept C2910938049 @default.
• W2117274465 hasConcept C29537977 @default.
• W2117274465 hasConcept C502942594 @default.
• W2117274465 hasConcept C54355233 @default.
• W2117274465 hasConcept C55493867 @default.
• W2117274465 hasConcept C62112901 @default.
• W2117274465 hasConcept C71924100 @default.
• W2117274465 hasConcept C86803240 @default.
• W2117274465 hasConceptScore W2117274465C121608353 @default.
• W2117274465 hasConceptScore W2117274465C126322002 @default.
• W2117274465 hasConceptScore W2117274465C142724271 @default.
• W2117274465 hasConceptScore W2117274465C146357865 @default.
• W2117274465 hasConceptScore W2117274465C151730666 @default.
• W2117274465 hasConceptScore W2117274465C190283241 @default.
• W2117274465 hasConceptScore W2117274465C196795494 @default.
• W2117274465 hasConceptScore W2117274465C204232928 @default.
• W2117274465 hasConceptScore W2117274465C2775975398 @default.
• W2117274465 hasConceptScore W2117274465C2777751288 @default.
• W2117274465 hasConceptScore W2117274465C2778019345 @default.
• W2117274465 hasConceptScore W2117274465C2779013556 @default.
• W2117274465 hasConceptScore W2117274465C2910938049 @default.
• W2117274465 hasConceptScore W2117274465C29537977 @default.
• W2117274465 hasConceptScore W2117274465C502942594 @default.
• W2117274465 hasConceptScore W2117274465C54355233 @default.

• next