Matches in SemOpenAlex for { <https://semopenalex.org/work/W2117293537> ?p ?o ?g. }
- W2117293537 endingPage "2176" @default.
- W2117293537 startingPage "2167" @default.
- W2117293537 abstract "The purpose of the present study was to investigate the relationship between in-stent neoatherosclerosis (NA) and native atherosclerosis progression of untreated coronary segments.In-stent NA was assessed by optical coherence tomography (OCT) among patients included in the SIRTAX-LATE OCT study 5 years after drug-eluting stent (DES) (sirolimus-eluting and paclitaxel-eluting stents) implantation. Neoatherosclerosis was defined as the presence of fibroatheroma or fibrocalcific plaque within the neointima of stented segments with a longitudinal extension >1.0 mm. Atherosclerosis progression in untreated native coronary segments was evaluated by serial quantitative coronary angiography (QCA). The change in minimal lumen diameter (MLD) was serially assessed within matched segments at baseline and 5-year angiographic follow-up. The key clinical endpoint was non-target lesion (non-TL) revascularization throughout 5 years. A total of 88 patients with 88 lesions were available for OCT analysis 5 years after DES implantation. In-stent NA was observed in 16% of lesions with the majority of plaques being fibroatheromas (11.4%) followed by fibrocalcific plaques (5.7%). A total of 704 non-TL segments were serially evaluated by QCA. Between baseline and 5-year follow-up, the reduction in MLD was significantly more pronounced in patients with NA (-0.25 mm, 95% CI -0.36 to -0.17 mm) when compared with patients without NA (-0.13 mm, 95% CI -0.17 to -0.10 mm, P = 0.002). Similarly, non-TL revascularization was more frequent in patients with NA (78.6%) when compared with patients without NA (44.6%, P = 0.028) throughout 5 years.In-stent NA is more common among patients with angiographic and clinical evidence of native atherosclerosis progression suggesting similar pathophysiological mechanisms.SIRTAX trial is registered at http://www.clinicaltrials.gov/ct2/show/NCT00617084." @default.
- W2117293537 created "2016-06-24" @default.
- W2117293537 creator A5035600962 @default.
- W2117293537 creator A5038409870 @default.
- W2117293537 creator A5040134218 @default.
- W2117293537 creator A5041250456 @default.
- W2117293537 creator A5047690226 @default.
- W2117293537 creator A5053194091 @default.
- W2117293537 creator A5071506939 @default.
- W2117293537 creator A5077441013 @default.
- W2117293537 creator A5088511695 @default.
- W2117293537 creator A5090901073 @default.
- W2117293537 date "2015-06-03" @default.
- W2117293537 modified "2023-09-27" @default.
- W2117293537 title "The association between in-stent neoatherosclerosis and native coronary artery disease progression: a long-term angiographic and optical coherence tomography cohort study" @default.
- W2117293537 cites W146325010 @default.
- W2117293537 cites W1853821798 @default.
- W2117293537 cites W1956305767 @default.
- W2117293537 cites W1976886356 @default.
- W2117293537 cites W1977835091 @default.
- W2117293537 cites W1990923081 @default.
- W2117293537 cites W1995394874 @default.
- W2117293537 cites W1997207240 @default.
- W2117293537 cites W2020417508 @default.
- W2117293537 cites W2055369987 @default.
- W2117293537 cites W2061556888 @default.
- W2117293537 cites W2068645948 @default.
- W2117293537 cites W2126846398 @default.
- W2117293537 cites W2134343469 @default.
- W2117293537 cites W44186969 @default.
- W2117293537 doi "https://doi.org/10.1093/eurheartj/ehv227" @default.
- W2117293537 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26040806" @default.
- W2117293537 hasPublicationYear "2015" @default.
- W2117293537 type Work @default.
- W2117293537 sameAs 2117293537 @default.
- W2117293537 citedByCount "72" @default.
- W2117293537 countsByYear W21172935372015 @default.
- W2117293537 countsByYear W21172935372016 @default.
- W2117293537 countsByYear W21172935372017 @default.
- W2117293537 countsByYear W21172935372018 @default.
- W2117293537 countsByYear W21172935372019 @default.
- W2117293537 countsByYear W21172935372020 @default.
- W2117293537 countsByYear W21172935372021 @default.
- W2117293537 countsByYear W21172935372022 @default.
- W2117293537 countsByYear W21172935372023 @default.
- W2117293537 crossrefType "journal-article" @default.
- W2117293537 hasAuthorship W2117293537A5035600962 @default.
- W2117293537 hasAuthorship W2117293537A5038409870 @default.
- W2117293537 hasAuthorship W2117293537A5040134218 @default.
- W2117293537 hasAuthorship W2117293537A5041250456 @default.
- W2117293537 hasAuthorship W2117293537A5047690226 @default.
- W2117293537 hasAuthorship W2117293537A5053194091 @default.
- W2117293537 hasAuthorship W2117293537A5071506939 @default.
- W2117293537 hasAuthorship W2117293537A5077441013 @default.
- W2117293537 hasAuthorship W2117293537A5088511695 @default.
- W2117293537 hasAuthorship W2117293537A5090901073 @default.
- W2117293537 hasBestOaLocation W21172935371 @default.
- W2117293537 hasConcept C126322002 @default.
- W2117293537 hasConcept C126838900 @default.
- W2117293537 hasConcept C131631996 @default.
- W2117293537 hasConcept C164705383 @default.
- W2117293537 hasConcept C203092338 @default.
- W2117293537 hasConcept C2776931568 @default.
- W2117293537 hasConcept C2777339539 @default.
- W2117293537 hasConcept C2777546689 @default.
- W2117293537 hasConcept C2778213512 @default.
- W2117293537 hasConcept C2778283817 @default.
- W2117293537 hasConcept C2778583881 @default.
- W2117293537 hasConcept C2778818243 @default.
- W2117293537 hasConcept C2779464278 @default.
- W2117293537 hasConcept C2779983491 @default.
- W2117293537 hasConcept C2780400711 @default.
- W2117293537 hasConcept C2781464078 @default.
- W2117293537 hasConcept C500558357 @default.
- W2117293537 hasConcept C535046627 @default.
- W2117293537 hasConcept C71924100 @default.
- W2117293537 hasConceptScore W2117293537C126322002 @default.
- W2117293537 hasConceptScore W2117293537C126838900 @default.
- W2117293537 hasConceptScore W2117293537C131631996 @default.
- W2117293537 hasConceptScore W2117293537C164705383 @default.
- W2117293537 hasConceptScore W2117293537C203092338 @default.
- W2117293537 hasConceptScore W2117293537C2776931568 @default.
- W2117293537 hasConceptScore W2117293537C2777339539 @default.
- W2117293537 hasConceptScore W2117293537C2777546689 @default.
- W2117293537 hasConceptScore W2117293537C2778213512 @default.
- W2117293537 hasConceptScore W2117293537C2778283817 @default.
- W2117293537 hasConceptScore W2117293537C2778583881 @default.
- W2117293537 hasConceptScore W2117293537C2778818243 @default.
- W2117293537 hasConceptScore W2117293537C2779464278 @default.
- W2117293537 hasConceptScore W2117293537C2779983491 @default.
- W2117293537 hasConceptScore W2117293537C2780400711 @default.
- W2117293537 hasConceptScore W2117293537C2781464078 @default.
- W2117293537 hasConceptScore W2117293537C500558357 @default.
- W2117293537 hasConceptScore W2117293537C535046627 @default.
- W2117293537 hasConceptScore W2117293537C71924100 @default.
- W2117293537 hasIssue "32" @default.
- W2117293537 hasLocation W21172935371 @default.
- W2117293537 hasLocation W21172935372 @default.