Matches in SemOpenAlex for { <https://semopenalex.org/work/W2117296500> ?p ?o ?g. }
- W2117296500 endingPage "947" @default.
- W2117296500 startingPage "940" @default.
- W2117296500 abstract "Chitosan, a deacetylated form of chitin, is a dietary fibre known for its hypolipidemic properties, which are mainly attributed to its unique cationic characteristics. We studied the selective in vivo effect of chitosan on fat excretion in order to elucidate its hypolipidemic mechanism. A 4-week longitudinal study was conducted in guinea pigs and the effect of chitosan on fat-absorption was compared to that of a soluble fibre: digestion-resistant maltodextrin. Animals were fed with high-fat isocaloric diets containing 12/100 g of cellulose, digestion-resistant maltodextrin or chitosan. Subsequently, the excretion of fatty acids, neutral sterols and bile acids was determined. Chitosan selectively reduced fat absorption in comparison to digestion-resistant maltodextrin. The excretion of lauric, myristic and palmitic fatty acids of animals fed with chitosan was more than 10-, 5- and 2-fold higher, respectively, than in the cellulose group, whereas stearic acid excretion was not significantly altered. Oleic, linoleic and α-linolenic acid excretion were also significantly higher (P < 0.001). The n−6/n−3 ratio in faeces of the chitosan group was 23.68, compared to 13.95 in the cellulose group. Total neutral sterol excretion was increased by both dietary fibres, whereas bile acid excretion was only increased by chitosan. Nevertheless, chitosan inhibited the intestinal bioconversion of cholesterol and primary bile acids to secondary metabolites. Hence, these results reveal that chitosan and digestion resistant maltodextrin exert their hypolipidemic activity by different mechanisms." @default.
- W2117296500 created "2016-06-24" @default.
- W2117296500 creator A5039460330 @default.
- W2117296500 creator A5044431149 @default.
- W2117296500 creator A5077681736 @default.
- W2117296500 creator A5054341605 @default.
- W2117296500 date "2012-09-01" @default.
- W2117296500 modified "2023-10-15" @default.
- W2117296500 title "Selective in vivo effect of chitosan on fatty acid, neutral sterol and bile acid excretion: A longitudinal study" @default.
- W2117296500 cites W1481290542 @default.
- W2117296500 cites W1913168986 @default.
- W2117296500 cites W1933119692 @default.
- W2117296500 cites W1961576110 @default.
- W2117296500 cites W1964774899 @default.
- W2117296500 cites W1968528693 @default.
- W2117296500 cites W1975299615 @default.
- W2117296500 cites W1978951971 @default.
- W2117296500 cites W1983519516 @default.
- W2117296500 cites W1991205326 @default.
- W2117296500 cites W1998826672 @default.
- W2117296500 cites W2023043844 @default.
- W2117296500 cites W2030816378 @default.
- W2117296500 cites W2035908943 @default.
- W2117296500 cites W2037980216 @default.
- W2117296500 cites W2047737201 @default.
- W2117296500 cites W2048012004 @default.
- W2117296500 cites W2057253426 @default.
- W2117296500 cites W2060412928 @default.
- W2117296500 cites W2065492479 @default.
- W2117296500 cites W2071803941 @default.
- W2117296500 cites W2079190053 @default.
- W2117296500 cites W2082023865 @default.
- W2117296500 cites W2096781687 @default.
- W2117296500 cites W2105953302 @default.
- W2117296500 cites W2112288125 @default.
- W2117296500 cites W2116859390 @default.
- W2117296500 cites W2130548465 @default.
- W2117296500 cites W2131991255 @default.
- W2117296500 cites W2146951052 @default.
- W2117296500 cites W2151702576 @default.
- W2117296500 cites W2158697874 @default.
- W2117296500 cites W2263303453 @default.
- W2117296500 doi "https://doi.org/10.1016/j.foodchem.2012.02.211" @default.
- W2117296500 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23107711" @default.
- W2117296500 hasPublicationYear "2012" @default.
- W2117296500 type Work @default.
- W2117296500 sameAs 2117296500 @default.
- W2117296500 citedByCount "26" @default.
- W2117296500 countsByYear W21172965002013 @default.
- W2117296500 countsByYear W21172965002014 @default.
- W2117296500 countsByYear W21172965002015 @default.
- W2117296500 countsByYear W21172965002016 @default.
- W2117296500 countsByYear W21172965002017 @default.
- W2117296500 countsByYear W21172965002018 @default.
- W2117296500 countsByYear W21172965002019 @default.
- W2117296500 countsByYear W21172965002020 @default.
- W2117296500 countsByYear W21172965002021 @default.
- W2117296500 countsByYear W21172965002022 @default.
- W2117296500 countsByYear W21172965002023 @default.
- W2117296500 crossrefType "journal-article" @default.
- W2117296500 hasAuthorship W2117296500A5039460330 @default.
- W2117296500 hasAuthorship W2117296500A5044431149 @default.
- W2117296500 hasAuthorship W2117296500A5054341605 @default.
- W2117296500 hasAuthorship W2117296500A5077681736 @default.
- W2117296500 hasConcept C10146269 @default.
- W2117296500 hasConcept C185592680 @default.
- W2117296500 hasConcept C2777846834 @default.
- W2117296500 hasConcept C2779399885 @default.
- W2117296500 hasConcept C2779587474 @default.
- W2117296500 hasConcept C2779732960 @default.
- W2117296500 hasConcept C2780809830 @default.
- W2117296500 hasConcept C2781003072 @default.
- W2117296500 hasConcept C2781357212 @default.
- W2117296500 hasConcept C2781403372 @default.
- W2117296500 hasConcept C31903555 @default.
- W2117296500 hasConcept C43617362 @default.
- W2117296500 hasConcept C543025807 @default.
- W2117296500 hasConcept C55493867 @default.
- W2117296500 hasConceptScore W2117296500C10146269 @default.
- W2117296500 hasConceptScore W2117296500C185592680 @default.
- W2117296500 hasConceptScore W2117296500C2777846834 @default.
- W2117296500 hasConceptScore W2117296500C2779399885 @default.
- W2117296500 hasConceptScore W2117296500C2779587474 @default.
- W2117296500 hasConceptScore W2117296500C2779732960 @default.
- W2117296500 hasConceptScore W2117296500C2780809830 @default.
- W2117296500 hasConceptScore W2117296500C2781003072 @default.
- W2117296500 hasConceptScore W2117296500C2781357212 @default.
- W2117296500 hasConceptScore W2117296500C2781403372 @default.
- W2117296500 hasConceptScore W2117296500C31903555 @default.
- W2117296500 hasConceptScore W2117296500C43617362 @default.
- W2117296500 hasConceptScore W2117296500C543025807 @default.
- W2117296500 hasConceptScore W2117296500C55493867 @default.
- W2117296500 hasIssue "2" @default.
- W2117296500 hasLocation W21172965001 @default.
- W2117296500 hasLocation W21172965002 @default.
- W2117296500 hasOpenAccess W2117296500 @default.
- W2117296500 hasPrimaryLocation W21172965001 @default.
- W2117296500 hasRelatedWork W117835969 @default.